Publication Name	World Journal of Hepatology
Manuscript ID	113458
Country	Brazil

Category	Gastroenterology & Hepatology
Manuscript Type	Observational Study
Article Title	Poor performance of strength, assistance with walking, rising from a chair, climbing stairs and falls for sarcopenia screening in cirrhosis: A pilot study
Manuscript Source	Invited Manuscript
All Author List	Bruna Goularth Lacerda, Luis F Ferreira, Lilian Kethelyn Teixeira Pinheiro, Claudio A Marroni and Sabrina Alves Fernandes
Funding Agency and Grant Number
Corresponding Author	Sabrina Alves Fernandes, PhD, Researcher, Program in Hepatology, Universidade Federal de Ciências da Saúde de Porto Alegre, Sarmento Leite 245, Porto Alegre 90050-170, Rio Grande do Sul, Brazil. sabrinaafernandes@gmail.com
Key Words	Liver cirrhosis; Sarcopenia; Nutritional status; Screening instruments; Hand strength
Core Tip	Sarcopenia is common in cirrhosis and negatively affects prognosis. Early detection is essential for effective management. We evaluated the strength, assistance with walking, rising from a chair, climbing stairs and falls (SARC-F) questionnaire as a screening tool in 45 cirrhotic patients. We compared its performance with objective functional tests, including handgrip strength and the Five times sit-to-stand test. Our main finding is that SARC-F significantly underperformed, missing all true positive cases and showing low sensitivity. In contrast, functional tests detected more patients at risk and proved more reliable. This indicates that SARC-F should not be used alone in cirrhotic patients. Functional assessments provide better guidance and should be integrated into clinical screening protocols.
Citation	Lacerda BG, Ferreira LF, Pinheiro LKT, Marroni CA, Fernandes SA. Poor performance of strength, assistance with walking, rising from a chair, climbing stairs and falls for sarcopenia screening in cirrhosis: A pilot study. World J Hepatol 2026; In press

Received	2025-08-26 03:28
Peer-Review Started	2025-08-26 03:28
First Decision by Editorial Office Director	2025-09-20 02:07
Return for Revision	2025-09-20 02:07
Revised	2025-12-17 03:58
Publication Fee Transferred
Second Decision by Editor	2026-02-10 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-02-10 08:58
Articles in Press	2026-02-10 08:58
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5182 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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