Publication Name	World Journal of Psychiatry
Manuscript ID	113487
Country	South Korea

Category	Psychiatry
Manuscript Type	Letter to the Editor
Article Title	Decoding auditory hallucinations with brain blood flow patterns?
Manuscript Source	Unsolicited Manuscript
All Author List	Haewon Byeon
Funding Agency and Grant Number	Funding Agency Grant Number National Research Foundation of Korea RS-2023-00237287
Corresponding Author	Haewon Byeon, Associate Professor, Director, PhD, Worker's Care & Digital Health Lab, Department of Future Technology, Korea University of Technology and Education, 1600, Chungjeol-ro, Cheonan 31253, South Korea. bhwpuma@naver.com
Key Words	Auditory verbal hallucinations; Transcranial Doppler; Nomogram; Cerebral hemodynamics; Differential diagnosis
Core Tip	This letter highlights the groundbreaking study by Cai et al, which uses an accessible tool to differentiate the causes of auditory verbal hallucinations. The researchers employed transcranial Doppler to find distinct brain blood flow patterns (hemodynamic signatures) in auditory verbal hallucinations across schizophrenia, post-traumatic stress disorder, and depression. While this is a promising proof-of-concept, the findings are preliminary due to the study’s retrospective, single-center design and the potential for medication-related confounding. For widespread clinical use, the models must be validated in larger, more diverse patient populations.
Citation	Byeon H. Decoding auditory hallucinations with brain blood flow patterns? World J Psychiatry 2025; In press

Received	2025-08-27 10:20
Peer-Review Started	2025-08-27 10:21
First Decision by Editorial Office Director	2025-09-12 03:03
Return for Revision	2025-09-12 03:03
Revised	2025-09-12 12:10
Publication Fee Transferred
Second Decision by Editor	2025-12-11 02:44
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-11 10:41
Articles in Press	2025-12-11 10:41
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3206 (online)
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