Publication Name	World Journal of Gastrointestinal Pathophysiology
Manuscript ID	113488
Country	India

Category	Ophthalmology
Manuscript Type	Systematic Reviews
Article Title	Role of gut microbiomes in different ocular pathologies: A systematic review
Manuscript Source	Invited Manuscript
All Author List	Priyanka Priyanka, Srishti Khullar, Mamta Singh, Arvind Kumar Morya, Bhavana Sharma, Brindha Periasamy, Bruttendu Moharana and Rannusha Morya
Funding Agency and Grant Number
Corresponding Author	Arvind Kumar Morya, MD, Professor, Senior Researcher, Department of Ophthalmology, All India Institute of Medical Sciences, Bibi Nagar, Hyderabad 508126, Telangana, India. bulbul.morya@gmail.com
Key Words	Gut microbiome; Ocular diseases; Dysbiosis; Gut-eye axis; Genomics; Prebiotics; Probiotics
Core Tip	The gut microbiome significantly influences ocular health through immune modulation, metabolic interactions, and maintenance of physiological barriers. Dysbiosis is linked to the onset and progression of major eye diseases such as uveitis, macular degeneration, dry eye, and glaucoma. Therapeutic interventions—including prebiotics, probiotics, synbiotics, and fecal microbiota transplantation—show promising results in preclinical and preliminary human studies, although further large-scale clinical trials are warranted to confirm their efficacy and safety in the context of ocular disease management.
Citation	Priyanka P, Khullar S, Singh M, Morya AK, Sharma B, Periasamy B, Moharana B, Morya R. Role of gut microbiomes in different ocular pathologies: A systematic review. World J Gastrointest Pathophysiol 2025; In press

Received	2025-08-27 16:23
Peer-Review Started	2025-08-28 00:08
First Decision by Editorial Office Director	2025-09-09 10:00
Return for Revision	2025-09-09 10:00
Revised	2025-09-21 14:35
Publication Fee Transferred
Second Decision by Editor	2025-12-02 02:46
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-02 09:07
Articles in Press	2025-12-02 09:07
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2150-5330 (online)
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