Publication Name	World Journal of Clinical Cases
Manuscript ID	113560
Country	Japan

Category	Toxicology
Manuscript Type	Case Report
Article Title	Severe venlafaxine poisoning successfully rescued with veno-arterial extracorporeal membrane oxygenation: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	kurumi Mori, Yoshito Kamijo, Tomoki Doi, Hiroko Abe and Ichiro Takeuchi
Funding Agency and Grant Number
Corresponding Author	kurumi Mori, Department of Emergency and Critical Care Medicine, Yokohama City University Medical Center, 4-57 Urafune-cho, Minami-ku, Yokohama 232-0024, Kanagawa, Japan. e123082b@yokohama-cu.ac.jp
Key Words	Venlafaxine; Massive ingestion; QTc prolongation; Veno-arterial extracorporeal membrane oxygenation; Ventricular fibrillation; Case report
Core Tip	A 31-year-old woman ingested a massive dose of venlafaxine (14.8 g) and initially showed only mild QTc prolongation. However, she developed ventricular fibrillation 15 hours post-ingestion. She was successfully managed with veno-arterial extracorporeal membrane oxygenation (VA-ECMO). This case highlights the potential for delayed but life-threatening cardiotoxicity in venlafaxine overdose and demonstrates the utility of VA-ECMO as a life-saving intervention. Continuous electrocardiographic monitoring beyond the early phase is essential even when initial findings are mild.
Citation	Mori K, Kamijo Y, Doi T, Abe H, Takeuchi I. Severe venlafaxine poisoning successfully rescued with veno-arterial extracorporeal membrane oxygenation: A case report. World J Clin Cases 2025; In press

Received	2025-08-29 05:36
Peer-Review Started	2025-08-29 05:36
To Make the First Decision
Return for Revision	2025-09-12 06:32
Revised	2025-09-25 08:34
Second Decision	2025-11-05 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-11-05 05:49
Articles in Press	2025-11-05 05:49
Publication Fee Transferred	2025-09-26 05:24
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2307-8960 (online)
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