Publication Name	World Journal of Gastrointestinal Endoscopy
Manuscript ID	113617
Country	Italy

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Role of endoscopic ultrasound in the treatment of pancreatic neuroendocrine tumors: Lights and shadows of endoscopic ultrasound-guided radiofrequency ablation
Manuscript Source	Invited Manuscript
All Author List	Alberto Tringali and Anna Caiazzo
Funding Agency and Grant Number
Corresponding Author	Alberto Tringali, Assistant Professor, Chief, Honorary Research Fellow, Lecturer, MD, PhD, Department of Digestive Endoscopy and Gastroenterology, Unità Locale di Sanità e Sociale 2, Conegliano Hospital, Via Brigata Bisagno, Conegliano 31015, Veneto, Italy. albtri10@gmail.com
Key Words	Pancreatic neuroendocrine tumor; Endoscopic ultrasound; Radiofrequency ablation; Loco-regional ablation; Guided radiofrequency ablation
Core Tip	In recent years, endoscopic ultrasound (EUS)-guided radiofrequency ablation (RFA) has become a subject of great interest in Digestive Endoscopy as locoregional treatment for pancreatic neoplastic lesions, particularly for pancreatic neoplastic cysts, pancreatic functional and non-functional neuroendocrine neoplasms and pancreatic ductal adenocarcinoma. The EUS-RFA procedure can potentially ablate these lesions locally in a minimally invasive manner with a very good safety profile. Our focus was to highlight the role of EUS-RFA in the treatment of pancreatic neuroendocrine tumors, based on available evidence, and describe the current potential benefits and limitations of this approach.
Citation	Tringali A, Caiazzo A. Role of endoscopic ultrasound in the treatment of pancreatic neuroendocrine tumors: Lights and shadows of endoscopic ultrasound-guided radiofrequency ablation. World J Gastrointest Endosc 2025; In press

Received	2025-08-29 09:06
Peer-Review Started	2025-08-29 09:06
To Make the First Decision
Return for Revision	2025-09-08 09:55
Revised	2025-09-19 17:12
Second Decision	2025-11-24 02:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-11-24 10:02
Articles in Press	2025-11-24 10:02
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5190 (online)
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