Publication Name	World Journal of Transplantation
Manuscript ID	113633
Country	United States

Category	Transplantation
Manuscript Type	Minireviews
Article Title	Nail abnormalities in upper extremity transplantation: Perspectives and insights from systemic diseases and organ transplantation
Manuscript Source	Unsolicited Manuscript
All Author List	Naga Anvesh Kodali, Ramu Janarthanan, Zeynep Demir, Bedreddin Sazoglu, Omer Faruk Dirican, Dmitry Tuder, Fatih Zor, Yalcin Kulahci and Vijay S Gorantla
Funding Agency and Grant Number
Corresponding Author	Yalcin Kulahci, Assistant Professor, MD, Department of Surgery, Advocate Health, Wake Forest University School of Medicine, 391 Technology Way NE, Winston-Salem, NC 27101, United States. yalcin.kulahci@advocatehealth.org
Key Words	Vascularized composite allotransplantation; Upper extremity transplantation; Hand transplantation; Nail abnormalities; Onychodystrophy; Graft rejection; Nailfold capillaroscopy
Core Tip	Nail changes after upper extremity transplantation (UET) are often overlooked but may represent early and atypical signs of graft rejection. This review synthesizes evidence from vascularized composite allotransplantation, systemic diseases, and solid organ transplantation, highlighting the diagnostic and prognostic value of nail abnormalities. By recognizing patterns such as onychomadesis, dystrophy, and nailfold capillary changes, clinicians can improve surveillance and timely intervention, ultimately enhancing long-term outcomes in UET recipients.
Citation	Kodali NA, Janarthanan R, Demir Z, Sazoglu B, Dirican OF, Tuder D, Zor F, Kulahci Y, Gorantla VS. Nail abnormalities in upper extremity transplantation: Perspectives and insights from systemic diseases and organ transplantation. World J Transplant 2025; In press

Received	2025-08-31 05:56
Peer-Review Started	2025-08-31 05:56
To Make the First Decision
Return for Revision	2025-09-23 08:25
Revised	2025-10-06 15:29
Second Decision	2025-11-18 01:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-11-18 02:35
Articles in Press	2025-11-18 02:35
Publication Fee Transferred	2025-10-08 17:53
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ISSN	2220-3230 (online)
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