Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	113661
Country	China

Category	Oncology
Manuscript Type	Retrospective Study
Article Title	Clinical characteristics and prognostic analysis of three hundred and nineteen cases of primary gastrointestinal diffuse large B-cell lymphoma
Manuscript Source	Unsolicited Manuscript
All Author List	Jia-Jia Ma, Huan Zhang, Cui-Cui Wang, Wen-Li Ji, Ying Zhao and Xin-Xia Li
Funding Agency and Grant Number	Funding Agency Grant Number Natural Science Foundation of Xinjiang Uygur Autonomous Region No. 2022D01D21 “Tianshan Talents” cultivation program of Xinjiang Uygur Autonomous Region No. 2024TSYCLJ0025 National Natural Science Foundation of China No. 82360037
Corresponding Author	Xin-Xia Li, Chief Physician, PhD, Professor, Pathology Center, Xinjiang Medical University Affiliated Tumor Hospital, No. 789 Suzhou East Street, Xinshi District, Urumqi 830000, Xinjiang Uygur Autonomous Region, China. lxxpatho@163.com
Key Words	Primary gastrointestinal diffuse large B-cell lymphoma; Clinical characteristics; Risk model; Non-germinal center B-cell-like subtype; Survival analysis; Prognosis
Core Tip	Primary gastrointestinal diffuse large B-cell lymphoma predominantly affects elderly men over 60 years, with abdominal pain, distension, and significant weight loss as common initial symptoms. Lesions are primarily located in the gastric body, antrum, and colon, often presenting as ulcerative or raised masses on endoscopy. Key independent prognostic risk factors include age > 60 years, presence of B symptoms, and elevated serum lactate dehydrogenase > 250 U/L, which correlate with poor survival outcomes and necessitate early diagnosis and targeted therapy.
Citation	Ma JJ, Zhang H, Wang CC, Ji WL, Zhao Y, Li XX. Clinical characteristics and prognostic analysis of three hundred and nineteen cases of primary gastrointestinal diffuse large B-cell lymphoma. World J Gastrointest Oncol 2025; In press

Received	2025-09-01 08:28
Peer-Review Started	2025-09-01 08:29
To Make the First Decision
Return for Revision	2025-09-07 02:54
Revised	2025-09-18 18:30
Second Decision	2025-11-05 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-11-05 07:03
Articles in Press	2025-11-05 07:03
Publication Fee Transferred	2025-09-23 15:36
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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