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Publication Name World Journal of Hepatology
Manuscript ID 113686
Country Thailand
Category Gastroenterology & Hepatology
Manuscript Type Minireviews
Article Title Epstein-Barr virus infection in children with liver transplantation
Manuscript Source Invited Manuscript
All Author List Norrapat Onpoaree, Nattinee Leelakanok, Anapat Sanpavat and Palittiya Sintusek
Funding Agency and Grant Number
Corresponding Author Palittiya Sintusek, Associate Professor, PhD, Center of Excellence in Thai Pediatric Gastroenterology, Hepatology and Immunology, Division of Gastroenterology, Department of Pediatrics, King Chulalongkorn Memorial Hospital, Chulalongkorn University, 1873 Rama IV, Pathumwan, Bangkok 10330, Thailand. palittiya.s@chula.ac.th
Key Words Epstein-Barr virus; Liver transplantation; Infection; Children; Post-transplant lymphoproliferative disorder; Lymphoma; Pediatric; Immunosuppressive drug; Immunocompromised; Rituximab
Core Tip Epstein-Barr virus (EBV) infection is common and can cause serious complications in pediatric liver transplant recipients. Young EBV-seronegative children are especially at increased risk because primary infection or viral reactivation may progress to post-transplant lymphoproliferative disorder. Routine EBV viral load monitoring, timely immunosuppressive therapy adjustment, and early intervention are crucial to reducing morbidity and mortality. A deeper understanding of EBV pathogenesis, combined with individualized management strategies, is essential for improving long-term outcomes in this high-risk population.
Citation Onpoaree N, Leelakanok N, Sanpavat A, Sintusek P. Epstein-Barr virus infection in children with liver transplantation. World J Hepatol 2025; In press
Received
2025-09-01 05:56
Peer-Review Started
2025-09-01 05:56
First Decision by Editorial Office Director
2025-09-08 09:56
Return for Revision
2025-09-08 09:56
Revised
2025-09-28 16:30
Publication Fee Transferred
Second Decision by Editor
2025-12-16 02:44
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-16 11:50
Articles in Press
2025-12-16 11:50
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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