Publication Name	World Journal of Clinical Cases
Manuscript ID	113778
Country	Ethiopia

Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Hepatic fascioliasis of emphasizing diagnostic difficulty and the need for high index of suspicion: Four case reports
Manuscript Source	Unsolicited Manuscript
All Author List	Sebhatleab T Mulate, Bishaw D Gesese, Abdulsemed Mohammed Nur, Hiwot B Mengistu, Rodas T Annose, Anteneh E Berga and Aga L Ulfata
Funding Agency and Grant Number
Corresponding Author	Sebhatleab T Mulate, Assistant Professor, MD, Department of Internal Medicine, Addis Ababa University, College of Health Science, Zambia Street, Addis Ababa 9086, Ethiopia. sebmulate@gmail.com
Key Words	Hepatic Fasciola; Neglected tropical disease; Vasculitis; Liver abscess; Triclabendazole; Nitazoxanide; Eosinophilia; Ethiopia; Case report
Core Tip	Hepatic fascioliasis remains a significant yet under-recognized cause of morbidity, particularly in endemic regions. Its variable presentations, prolonged clinical course, and limited clinician awareness—coupled with constrained access to serologic testing—often lead to misdiagnosis (e.g., as malignancy or bacterial abscess). This results in unnecessary costs and delayed treatment. A high index of clinical suspicion, a thorough inquiry about exposure and travel history, recognition of characteristic imaging findings, and correlation with eosinophilia are critical for a timely diagnosis. Early empiric treatment, which is simple and cost-effective, can prevent invasive procedures and reduce the patient burden.
Citation	Mulate ST, Gesese BD, Nur AM, Mengistu HB, Annose RT, Berga AE, Ulfata AL. Hepatic fascioliasis of emphasizing diagnostic difficulty and the need for high index of suspicion: Four case reports. World J Clin Cases 2025; In press

Received	2025-09-03 08:57
Peer-Review Started	2025-09-03 08:57
First Decision by Editorial Office Director	2025-10-10 09:24
Return for Revision	2025-10-10 14:10
Revised	2025-10-24 08:46
Publication Fee Transferred
Second Decision by Editor	2025-12-08 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-08 08:26
Articles in Press	2025-12-08 08:26
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2307-8960 (online)
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