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Publication Name World Journal of Gastroenterology
Manuscript ID 113804
Country China
Category Food Science & Technology
Manuscript Type Review
Article Title High-protein diets and metabolic dysfunction-associated steatotic liver disease: A double-edged sword in liver health
Manuscript Source Unsolicited Manuscript
All Author List Hong-Yuan Yin, Qian-Hui You, Wei-Jie Zhang, Guang Ji and Yan-Qi Dang
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 82320108022
Corresponding Author Yan-Qi Dang, Institute of Digestive Diseases, Longhua Hospital, China-Canada Center of Research for Digestive Diseases, Shanghai University of Traditional Chinese Medicine, Fenglin Road Sub-District, Shanghai 200032, China. dangyanqi9022@126.com
Key Words High-protein diets; Metabolic dysfunction-associated steatotic liver disease; Diet; Mechanism; Clinical trial
Core Tip High-protein diets have dual effects on metabolic dysfunction-associated steatotic liver disease, depending on protein source and amount. Plant-based proteins may benefit liver metabolism, inflammation, and gut microbiota, whereas excessive animal proteins could worsen outcomes. Metabolic dysfunction-associated steatotic liver disease patients should favor plant proteins and limit animal proteins; personalized dietary strategies require further mechanistic research.
Citation Yin HY, You QH, Zhang WJ, Ji G, Dang YQ. High-protein diets and metabolic dysfunction-associated steatotic liver disease: A double-edged sword in liver health. World J Gastroenterol 2025; In press
Received
2025-09-04 03:40
Peer-Review Started
2025-09-04 03:40
First Decision by Editorial Office Director
2025-10-13 09:25
Return for Revision
2025-10-13 09:25
Revised
2025-10-27 04:32
Publication Fee Transferred
2025-11-05 04:00
Second Decision by Editor
2025-12-09 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-09 09:50
Articles in Press
2025-12-09 09:50
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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