Publication Name	World Journal of Psychiatry
Manuscript ID	113893
Country	Türkiye

Category	Psychiatry
Manuscript Type	Letter to the Editor
Article Title	Lithium and valproic acid in bipolar disorder: Beyond mood stabilization - the overlooked role of sleep
Manuscript Source	Invited Manuscript
All Author List	Esra Kabadayi Sahin
Funding Agency and Grant Number
Corresponding Author	Esra Kabadayi Sahin, Associate Professor, MD, Department of Psychiatry, Ankara Yildirim Beyazit University Faculty of Medicine, Universiteler Mahallesi, Cankaya, Ankara 06800, Türkiye. ekabadayi06@gmail.com
Key Words	Mood stabilizers; Sleep; Wearable technologies; Bipolar disorder; Lithium; Valproate
Core Tip	This letter emphasizes the importance of evaluating sleep as a central physiological parameter in bipolar disorder. While the original study demonstrated lithium’s advantage over valproic acid in sleep quality. It is highlighted that reliance solely on self-reported scales is a limitation. Wearable technologies and actigraphy offer objective, scalable alternatives to polysomnography. Future studies should integrate serum drug-level monitoring and adjunctive antipsychotic data into longitudinal designs to clarify how mood stabilizers influence sleep and to advance personalized treatment strategies in bipolar disorder.
Citation	Kabadayi Sahin E. Lithium and valproic acid in bipolar disorder: Beyond mood stabilization - the overlooked role of sleep. World J Psychiatry 2025; In press

Received	2025-09-05 14:20
Peer-Review Started	2025-09-05 14:20
To Make the First Decision
Return for Revision	2025-09-16 07:30
Revised	2025-09-17 10:16
Second Decision	2025-10-11 02:46
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-10-11 10:37
Articles in Press	2025-10-11 10:37
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3206 (online)
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