Publication Name	World Journal of Stem Cells
Manuscript ID	113900
Country	Japan

Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Allogeneic myoblast cell sheet transplantation for esophageal wall reinforcement
Manuscript Source	Invited Manuscript
All Author List	Takahiro Enjoji, Shinichiro Kobayashi, Daisuke Miyamoto, Shinichiro Ogawa, Hanako Tetsuo, Akihiko Soyama, Tomohiko Adachi, Susumu Eguchi and Kengo Kanetaka
Funding Agency and Grant Number	Funding Agency Grant Number JSPS Grant-in-Aid for Scientific Research C 24K11935 AMED 25ym0126811j0004
Corresponding Author	Shinichiro Kobayashi, Associate Professor, FACS, MD, PhD, Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1, Sakamoto, Nagasaki 852-8501, Japan. skobayashi1980@gmail.com
Key Words	Myoblast; Esophagus; Muscle layer; Cell sheet; Tissue repair
Core Tip	Muscle flaps are widely used for reinforcing esophageal defects. However, they are invasive and cosmetically unfavorable. Myoblast cell sheets are less invasive, although their in vivo behavior is unclear. In a rat model of esophageal muscle layer defects, transplanted myoblast sheets formed multilayered desmin-positive and Ki67-positive structures and transiently increased esophageal wall thickness compared with controls that did not receive a myoblast cell sheet transplantation at 1 week. These findings suggested that myoblast cell sheets provide short-term reinforcement, highlighting their potential as muscle flap alternatives while underscoring the need for further evaluation.
Citation	Enjoji T, Kobayashi S, Miyamoto D, Ogawa S, Tetsuo H, Soyama A, Adachi T, Eguchi S, Kanetaka K. Allogeneic myoblast cell sheet transplantation for esophageal wall reinforcement. World J Stem Cells 2026; In press

Received	2025-09-07 07:12
Peer-Review Started	2025-09-07 07:12
First Decision by Editorial Office Director	2025-09-29 07:14
Return for Revision	2025-09-29 07:14
Revised	2025-10-25 08:13
Publication Fee Transferred
Second Decision by Editor	2026-01-26 05:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-02-03 02:23
Articles in Press	2026-02-03 02:23
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-0210 (online)
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