Publication Name	World Journal of Stem Cells
Manuscript ID	113930
Country	China

Category	Neurosciences
Manuscript Type	Letter to the Editor
Article Title	Synergetic pathways for Parkinson’s disease therapy: The intersection of exercise and stem cell science
Manuscript Source	Invited Manuscript
All Author List	An-Lin Zhang and Luan Wen
Funding Agency and Grant Number	Funding Agency Grant Number National College Students’ Innovation and Entrepreneurship Training Program in Hainan Medical University S202511810030
Corresponding Author	Luan Wen, PhD, Professor, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Hainan Medical University, No. 3 Xueyuan Road, Haikou 571199, Hainan Province, China. luanwen@muhn.edu.cn
Key Words	Parkinson’s disease; Induce pluripotent stem cells; Exercise; Dopaminergic differentiation; Neuronal repair
Core Tip	The most promising path forward for treating Parkinson’s disease may be through integrative therapies that synergistically combine regenerative medicine, such as stem cell transplants, with systemic interventions like exercise. This approach leverages exercise to prime the brain’s environment, thereby significantly enhancing the potential for cellular repair and urging a vital shift toward combined, interdisciplinary treatment strategies.
Citation	Zhang AL, Wen L. Synergetic pathways for Parkinson’s disease therapy: The intersection of exercise and stem cell science. World J Stem Cells 2026; In press

Received	2025-09-17 06:33
Peer-Review Started	2025-09-17 06:33
First Decision by Editorial Office Director	2025-10-17 07:22
Return for Revision	2025-10-17 07:22
Revised	2025-10-27 03:13
Publication Fee Transferred
Second Decision by Editor	2026-01-12 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-01-12 12:56
Articles in Press	2026-01-12 12:56
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-0210 (online)
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