Publication Name	World Journal of Diabetes
Manuscript ID	113947
Country	China

Category	Medicine, Research & Experimental
Manuscript Type	Basic Study
Article Title	SLC30A8 promoter hypermethylation is associated with type 2 diabetes and diabetic kidney disease in a Chinese population
Manuscript Source	Unsolicited Manuscript
All Author List	Nan Li, Yu-Peng Li, Qing Xu, Jian Xu, Yi-Hong Yu, Juan Su, Chong Shen, Jiang-Yi Yu and Harvest F Gu
Funding Agency and Grant Number	Funding Agency Grant Number Excellent Doctor Program of Jiangsu Province Hospital of Chinese Medicine 20221222 Launch Grant of China Pharmaceutical University 20180815
Corresponding Author	Harvest F Gu, Laboratory of Molecular Medicine, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, No. 24 Tongjia Alley, Gulou District, Nanjing 210009, Jiangsu Province, China. feng.gu@cpu.edu.cn
Key Words	Diabetic kidney disease; DNA methylation; Solute carrier family 30 member 8; Type 2 diabetes; Hypermethylation
Core Tip	Solute carrier family 30 member 8 (SLC30A8) is a β-cell specific Zn transporter in insulin secretory granules. DNA in the SLC30A8 gene promoter region is hypermethylated. SLC30A8 promoter hypermethylation is associated with both type 2 diabetes and diabetic kidney disease. This study aims to evaluate whether DNA methylation changes in SLC30A8 is associated with type 2 diabetes and diabetic kidney disease.
Citation	Li N, Li YP, Xu Q, Xu J, Yu YH, Su J, Shen C, Yu JY, Gu HF. SLC30A8 promoter hypermethylation is associated with type 2 diabetes and diabetic kidney disease in a Chinese population. World J Diabetes 2025; In press

Received	2025-09-08 06:24
Peer-Review Started	2025-09-12 00:15
First Decision by Editorial Office Director	2025-10-23 08:13
Return for Revision	2025-10-23 08:13
Revised	2025-10-25 10:36
Publication Fee Transferred
Second Decision by Editor	2025-12-18 02:52
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-25 07:59
Articles in Press	2025-12-25 07:59
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9358 (online)
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