Publication Name	World Journal of Nephrology
Manuscript ID	113952
Country	Türkiye

Category	Urology & Nephrology
Manuscript Type	Letter to the Editor
Article Title	Integrating Modified National Early Warning Score 2, computed tomography staging, and laboratory markers for enhanced prognostic stratification in emphysematous pyelonephritis
Manuscript Source	Unsolicited Manuscript
All Author List	Cagri Sevik, Akif Erbin and Halil Lutfi Canat
Funding Agency and Grant Number
Corresponding Author	Akif Erbin, Associate Professor, Department of Urology, Health Science University (Turkey), Basaksehir Çam and Sakura City Hospital, qq, Istanbul 34300, Türkiye. akiferbin@hotmail.com
Key Words	Emphysematous pyelonephritis; Modified National Early Warning Score 2; Computed tomography classification; Prognostic factors; Nephrectomy
Core Tip	Emphysematous pyelonephritis is a rapidly progressive and life-threatening infection that necessitates timely and precise prognostic evaluation. Although the Modified National Early Warning Score 2 provides valuable risk information based exclusively on physiological parameters, clinical deterioration typically manifests at a relatively advanced stage. In contrast, computed tomography based staging and critical laboratory indicators, including anemia, thrombocytopenia, leukocytosis, and hyperglycemia, may yield earlier prognostic insights before overt vital-sign abnormalities develop. A combined assessment incorporating Modified National Early Warning Score 2, computed tomography classification, and laboratory indicators may therefore improve early risk stratification, inform timely nephrectomy decisions in high-risk patients, and ultimately optimize clinical outcomes.
Citation	Sevik C, Erbin A, Canat HL. Integrating Modified National Early Warning Score 2, computed tomography staging, and laboratory markers for enhanced prognostic stratification in emphysematous pyelonephritis. World J Nephrol 2025; In press

Received	2025-09-09 10:05
Peer-Review Started	2025-09-09 10:05
First Decision by Editorial Office Director	2025-10-18 02:21
Return for Revision	2025-10-18 02:21
Revised	2025-10-20 09:41
Publication Fee Transferred
Second Decision by Editor	2025-12-25 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-25 06:49
Articles in Press	2025-12-25 06:49
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-6124 (online)
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