Publication Name	World Journal of Gastrointestinal Pathophysiology
Manuscript ID	113971
Country	India

Category	Gastroenterology & Hepatology
Manuscript Type	Case Control Study
Article Title	Frequency and predictors of fructose malabsorption in patients with functional abdominal pain syndrome: A case-control study
Manuscript Source	Invited Manuscript
All Author List	Mayank Agarwal, Venkatesh Vaithiyam, Ravi Teja Reddy, Payila Satya Raghava Aneesh, Prisha Paliwal, Sahil Rahul Jain, Ashok Dalal, Ajay Kumar, Amarender Singh Puri and Sanjeev Sachdeva
Funding Agency and Grant Number
Corresponding Author	Venkatesh Vaithiyam, Assistant Professor, Department of Gastroenterology, Govind Ballabh Pant Institute of Postgraduate Medical Education and Research, Jawahar Lal Nehru Marg, New Delhi 110002, Delhi, India. venkateshvaithiyam172@gmail.com
Key Words	Functional abdominal pain syndrome; Fructose malabsorption; Fructose hydrogen breath test; Fermentable oligo-, di-, and monosaccharides and polyols; Functional gastrointestinal disorder
Core Tip	This case-control study was carried out to evaluate the frequency of fructose malabsorption (FM) in adult patients with functional abdominal pain syndrome (FAPS) after systematically ruling out small intestinal bacterial overgrowth. We found that FM was significantly more common in patients with FAPS compared to healthy controls. Notably, some patients with FAPS reported fructose-related symptoms even without biochemical evidence of FM, which supports the role of visceral hypersensitivity. These findings highlight the potential advantages of dietary strategies, such as fermentable oligo-, di-, and monosaccharides and polyols restriction, in managing FAPS.
Citation	Agarwal M, Vaithiyam V, Reddy RT, Aneesh PSR, Paliwal P, Jain SR, Dalal A, Kumar A, Puri AS, Sachdeva S. Frequency and predictors of fructose malabsorption in patients with functional abdominal pain syndrome: A case-control study. World J Gastrointest Pathophysiol 2025; In press

Received	2025-09-09 03:01
Peer-Review Started	2025-09-09 03:01
First Decision by Editorial Office Director	2025-09-25 08:59
Return for Revision	2025-09-25 08:59
Revised	2025-10-06 13:08
Publication Fee Transferred
Second Decision by Editor	2025-12-18 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-18 08:18
Articles in Press	2025-12-18 08:18
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2150-5330 (online)
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