Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	113976
Country	China

Category	Oncology
Manuscript Type	Retrospective Study
Article Title	Prognostic significance of preoperative C-reactive protein-triglyceride-glucose index in long-term outcomes after radical gastrectomy for gastric cancer
Manuscript Source	Unsolicited Manuscript
All Author List	Qiu-Lin Hao, Zhi-Yuan Yao, Yu-Meng Shen, Zheng-Yu Li, Hao-Chun Gao, Xiao-Yu Hong, Geng-Chen Li and Chao Gao
Funding Agency and Grant Number
Corresponding Author	Chao Gao, MD, PhD, Professor, Department of Oncology, The Affiliated Hospital of Xuzhou Medical University, No. 99 Huaihai West Road, Xuzhou 221000, Jiangsu Province, China. gaochaoly@sina.com
Key Words	C-reactive protein triglyceride glucose index; Prognostic nutritional index; Gastric cancer; Prognostic model; Radical gastrectomy
Core Tip	Gastric cancer is the third leading cause of cancer-related mortality worldwide. Radical surgery remains the primary treatment for early-stage gastric cancer, but the overall survival rate post-surgery remains relatively low. Identifying key prognostic factors is essential to optimize treatment strategies. The C-reactive protein-triglyceride-glucose (CTI) index, which integrates both inflammatory and metabolic markers, has garnered increasing attention in cancer research, particularly in gastric cancer prognosis. However, few studies have explored the impact of CTI on cancer patient outcomes. Therefore, we conducted a retrospective clinical study to examine the influence of CTI on the prognosis of patients undergoing radical gastrectomy for gastric cancer and developed a corresponding predictive model. Additionally, we incorporated the prognostic nutritional index coefficient to improve the predictive accuracy of the model.
Citation	Hao QL, Yao ZY, Shen YM, Li ZY, Gao HC, Hong XY, Li GC, Gao C. Prognostic significance of preoperative C-reactive protein-triglyceride-glucose index in long-term outcomes after radical gastrectomy for gastric cancer. World J Gastrointest Oncol 2025; In press

Received	2025-09-09 02:36
Peer-Review Started	2025-09-09 02:38
To Make the First Decision
Return for Revision	2025-09-16 08:02
Revised	2025-09-26 14:02
Second Decision	2025-11-06 02:48
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-11-06 08:57
Articles in Press	2025-11-06 08:57
Publication Fee Transferred	2025-10-09 08:53
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Typeset the Manuscript

ISSN	1948-5204 (online)
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