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Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 114021
Country China
Category Oncology
Manuscript Type Case Report
Article Title Clinicopathologic features of SMARCB1/INI1-deficient pancreatic undifferentiated rhabdoid carcinoma: A case report and review of literature
Manuscript Source Unsolicited Manuscript
All Author List Wan-Qi Yao, Xin-Yi Ma and Gui-Hua Wang
Funding Agency and Grant Number
Corresponding Author Gui-Hua Wang, MD, Professor, Pathology, The First Affiliated Hospital of Zhejiang University School of Medicine, No.1260 Kangliang Street, Liangzhu Street, Hangzhou 311112, Zhejiang Province, China. mamaninghao@163.com
Key Words Chemotherapy; Switch/sucrose non-fermentable; Rhabdoid features; Spontaneous splenic rupture; SMARCB1/INI1; Pancreatic undifferentiated carcinoma; Case report
Core Tip SMARCB1-deficient undifferentiated rhabdoid carcinoma of the pancreas represents a highly aggressive and rare neoplasm. This study suggests that aggressive multimodal therapy, including surgical resection and chemotherapy, may prolong survival in selected patients; however, the overall prognosis remains poor. Given its distinct molecular characteristics and potential resistance to standard therapies, further research into targeted treatment approaches and prospective clinical studies is urgently warranted.
Citation Yao WQ, Ma XY, Wang GH. Clinicopathologic features of SMARCB1/INI1-deficient pancreatic undifferentiated rhabdoid carcinoma: A case report and review of literature. World J Gastrointest Oncol 2025; In press
Received
2025-09-11 02:05
Peer-Review Started
2025-09-11 02:05
First Decision by Editorial Office Director
2025-10-18 02:39
Return for Revision
2025-10-19 08:02
Revised
2025-11-02 00:33
Publication Fee Transferred
2025-11-07 01:00
Second Decision by Editor
2025-12-01 03:10
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-01 11:05
Articles in Press
2025-12-01 11:05
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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