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Publication Name World Journal of Transplantation
Manuscript ID 114044
Country Morocco
Category Transplantation
Manuscript Type Retrospective Study
Article Title Preformed vs de novo anti-human leukocyte antigens-DQ antibodies in kidney transplantation: A retrospective study
Manuscript Source Unsolicited Manuscript
All Author List Oumaima Guissouss, Khalid Achiaou, Joumana El Turk, Asmaa Mourachid, Abdelhadi Cheggali, Ghislaine Medkouri, Benyounes Ramdani, Mohammed Benghanem Gharbi, Majda Taoudi Benchekroun and Siham Bennani
Funding Agency and Grant Number
Funding Agency Grant Number
the National Science and Technology Research Center (Morocco) “PhD-Associate Scholarship - PASS” Program 88UH2C2023
Corresponding Author Oumaima Guissouss, Faculty of Sciences Ain Chock, Laboratory of Integrative Biology, University Hassan II, El Jadida Road, Casablanca 20100, Morocco. oumaima.guissouss-etu@etu.univh2c.ma / oumayma.guissouss1@gmail.com
Key Words Kidney transplantation; Donor-specific antibodies; De novo donor-specific antibodie; Human leukocyte antigens DQ; Antibody-mediated rejection; Banff classification; Morocco
Core Tip This retrospective study highlights the emerging role of donor-specific anti- human leukocyte antigen (HLA)-DQ antibodies in kidney transplantation, an area where evidence from Moroccan populations remains scarce. Individual cases illustrate the clinical spectrum, but the findings derive from a systematic retrospective analysis. The study highlights the association between anti-HLA-DQ antibodies, antibody-mediated rejection, and graft outcomes, underscoring the need to integrate HLA-DQ monitoring into routine post-transplant follow-up and offering a valuable perspective for improving patient management in resource-limited settings.
Citation Guissouss O, Achiaou K, El Turk J, Mourachid A, Cheggali A, Medkouri G, Ramdani B, Benghanem Gharbi M, Taoudi Benchekroun M, Bennani S. Preformed vs de novo anti-human leukocyte antigens-DQ antibodies in kidney transplantation: A retrospective study. World J Transplant 2025; In press
Received
2025-09-11 07:43
Peer-Review Started
2025-09-11 07:43
First Decision by Editorial Office Director
2025-09-17 08:31
Return for Revision
2025-09-17 08:31
Revised
2025-09-30 22:13
Publication Fee Transferred
2025-10-07 16:36
Second Decision by Editor
2025-12-02 02:46
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-03 04:07
Articles in Press
2025-12-03 04:07
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2220-3230 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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