Publication Name	World Journal of Psychiatry
Manuscript ID	114081
Country	China

Category	Psychiatry
Manuscript Type	Retrospective Cohort Study
Article Title	Association between depression, anxiety, and treatment adherence in patients with diabetic macular edema
Manuscript Source	Unsolicited Manuscript
All Author List	Yan-Ling Jin, Shi-Wei Li, Ya-Min Wang, Bin Lu, Xiang-Ning Wang and Da Long
Funding Agency and Grant Number	Funding Agency Grant Number Shanghai Sixth People's Hospital Retrospective Clinical Research Project (Lingang Special Project) No. ynhglg202522 Shanghai Sixth People’s Hospital Hospital-Level Clinical Research Project No. ynhglg202523 Shanghai Sixth People’s Hospital Hospital-Level Scientific Research Fund No.ynts 202213
Corresponding Author	Da Long, MD, Department of Ophthalmology, Shanghai Jiao Tong University Sixth People's Hospital, No. 600 Yishan Road, Shanghai 200233, China. sldyyk66@sina.com
Key Words	Diabetic macular edema; Depression; Anxiety; Treatment adherence; Visual function; Quality of life
Core Tip	Depression and anxiety are frequent psychiatric comorbidities in patients with diabetic macular edema (DME) and play a crucial role in treatment adherence. This retrospective study found that both disorders were strongly associated with poor medication compliance and reduced appointment attendance, ultimately leading to impaired visual outcomes and lower quality of life. Treatment adherence partially mediated the link between depression and vision loss. These findings underscore the need for integrated management strategies that combine psychiatric care with ophthalmological treatment to optimize adherence and improve clinical prognosis in DME.
Citation	Jin YL, Li SW, Wang YM, Lu B, Wang XN, Long D. Association between depression, anxiety, and treatment adherence in patients with diabetic macular edema. World J Psychiatry 2026; In press

Received	2025-10-10 08:30
Peer-Review Started	2025-10-10 08:31
First Decision by Editorial Office Director	2025-11-21 06:18
Return for Revision	2025-11-21 06:18
Revised	2025-11-29 16:12
Publication Fee Transferred	2025-12-03 09:12
Second Decision by Editor	2026-01-14 02:46
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-01-14 05:16
Articles in Press	2026-01-14 05:16
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3206 (online)
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