Publication Name	World Journal of Clinical Pediatrics
Manuscript ID	114152
Country	Pakistan

Category	Geriatrics & Gerontology
Manuscript Type	Letter to the Editor
Article Title	Mucopolysaccharidosis type VI in the Russian registry: Further insights and considerations
Manuscript Source	Invited Manuscript
All Author List	Sajid Malik
Funding Agency and Grant Number
Corresponding Author	Sajid Malik, PhD, Department of Zoology, Faculty of Biological Sciences, Quaid-I-Azam University, University Road, Islamabad 45320, Pakistan. malik@qau.edu.pk
Key Words	Mucopolysaccharidosis type VI; Metabolic disorder; Maroteaux-Lamy syndrome; Russian National registry; Genotype-phenotype correlation; Enzyme replacement therapy; Mutation
Core Tip	This commentary highlights major methodological and reporting limitations in the recent mucopolysaccharidosis type VI Russian national registry study by Vechkasova et al, including missing statistical analyses, unclear genotype-phenotype correlations, inconsistent data reporting, and survivorship bias. Improving data transparency, variant interpretation, and clinical documentation is essential for the registry to generate reliable insights and guide patient care.
Citation	Malik S. Mucopolysaccharidosis type VI in the Russian registry: Further insights and considerations. World J Clin Pediatr 2025; In press

Received	2025-09-15 02:39
Peer-Review Started	2025-09-15 02:39
First Decision by Editorial Office Director	2025-10-11 05:36
Return for Revision	2025-10-11 05:36
Revised	2025-10-17 17:28
Publication Fee Transferred
Second Decision by Editor	2025-12-16 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-16 11:10
Articles in Press	2025-12-16 11:10
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2219-2808 (online)
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