Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	114164
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Analysis of quality of life and reflux oesophagitis following Billroth II and Roux-en-Y gastrointestinal reconstruction for gastric cancer
Manuscript Source	Unsolicited Manuscript
All Author List	Xin-Xing Duan, Xiong Yu and Jin Gan
Funding Agency and Grant Number
Corresponding Author	Jin Gan, MD, General Surgery Center, Jiujiang City Key Laboratory of Cell Therapy, Jiujiang No. 1 People's Hospital, No. 48 Taling South Road, Xunyang District, Jiujiang 332000, Jiangxi Province, China. gj19863419@163.com
Key Words	Gastric cancer; Gastrointestinal reconstruction; Billroth II procedure; Roux-en-Y procedure; Quality of life; Reflux oesophagitis
Core Tip	This study demonstrates that compared to Billroth II reconstruction, Roux-en-Y anastomosis significantly reduces the incidence of gastroesophageal reflux and reflux esophagitis, alleviates reflux-related symptoms, and improves postoperative quality of life (QoL) in gastric cancer patients after radical distal gastrectomy. Although operative time may be longer with Roux-en-Y, it offers superior long-term functional outcomes by minimizing bile reflux and associated complications, without compromising nutritional status. Roux-en-Y reconstruction is recommended for its enhanced QoL benefits and reduced reflux morbidity.
Citation	Duan XX, Yu X, Gan J. Analysis of quality of life and reflux oesophagitis following Billroth II and Roux-en-Y gastrointestinal reconstruction for gastric cancer. World J Gastrointest Surg 2025; In press

Received	2025-09-15 12:58
Peer-Review Started	2025-09-15 12:59
To Make the First Decision
Return for Revision	2025-09-26 09:32
Revised	2025-10-09 08:00
Second Decision	2025-11-18 01:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-11-18 07:09
Articles in Press	2025-11-18 07:09
Publication Fee Transferred	2025-10-11 06:16
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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