Publication Name	World Journal of Gastroenterology
Manuscript ID	114222
Country	United States

Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Reducing agents for induction and maintenance therapy achieve long-term remission of refractory ulcerative colitis: A case report and review of literature
Manuscript Source	Unsolicited Manuscript
All Author List	Pamela B Sylvestre
Funding Agency and Grant Number
Corresponding Author	Pamela B Sylvestre, MD, Professor, Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, 240 Albert Sabin Way, MLC1035, Cincinnati, OH 45229, United States. sylvespa@ucmail.uc.edu
Key Words	Ulcerative colitis; Colitis; Inflammatory bowel disease; Hydrogen peroxide; Sodium thiosulfate; R-dihydrolipoic acid; Reducing agent; Redox homeostasis; Reactive oxygen species; Case report
Core Tip	Reducing agents, sodium thiosulfate and R-dihydrolipoic acid, are safe and highly effective to induce and maintain remission of ulcerative colitis, respectively, without the need for immunosuppressive drugs, even in patients who are refractory or poorly controlled by conventional and advanced therapies.
Citation	Sylvestre PB. Reducing agents for induction and maintenance therapy achieve long-term remission of refractory ulcerative colitis: A case report and review of literature. World J Gastroenterol 2025; In press

Received	2025-09-16 04:53
Peer-Review Started	2025-09-16 04:53
First Decision by Editorial Office Director	2025-10-30 09:24
Return for Revision	2025-10-30 09:24
Revised	2025-11-13 12:24
Publication Fee Transferred	2025-11-18 02:40
Second Decision by Editor	2025-12-02 02:46
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-03 03:22
Articles in Press	2025-12-03 03:22
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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