Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	114227
Country	Türkiye

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Cohort Study
Article Title	Admission hyperphosphatemia as a predictor of severity and mortality in acute pancreatitis: A 1000-patient cohort study
Manuscript Source	Unsolicited Manuscript
All Author List	Yavuz Özden and Nuh Mehmet Buyukberber
Funding Agency and Grant Number
Corresponding Author	Yavuz Özden, Department of Gastroenterology, Kayseri City Hospital, University of Health Sciences, Şeker District, Muhsin Yazıcıoğlu Boulevard No. 77 Kocasinan, Kayseri 38080, Türkiye. yavuzozden@gmail.com
Key Words	Acute pancreatitis; Serum phosphate; Hyperphosphatemia; Hypophosphatemia; Prognostic biomarker; Mortality; Intensive care unit; Cohort study
Core Tip	Early risk stratification in acute pancreatitis remains a major clinical challenge, as conventional scoring systems require up to 48 hours and limit decision-making in the emergency setting. In this large 1000-patient cohort, admission hyperphosphatemia was strongly associated with severe disease, pancreatic necrosis, intensive care requirement, and 30-day mortality and was identified as an independent predictor of poor outcomes. These findings suggest that serum phosphate is an inexpensive, readily available biomarker that may complement existing tools and enable the prompt identification of high-risk patients at hospital admission.
Citation	Özden Y, Buyukberber NM. Admission hyperphosphatemia as a predictor of severity and mortality in acute pancreatitis: A 1000-patient cohort study. World J Gastrointest Surg 2025; In press

Received	2025-09-16 03:46
Peer-Review Started	2025-09-16 03:46
To Make the First Decision
Return for Revision	2025-10-11 13:06
Revised	2025-10-22 15:01
Second Decision	2025-11-27 02:44
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-11-27 06:25
Articles in Press	2025-11-27 06:25
Publication Fee Transferred	2025-11-03 19:01
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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