Publication Name	World Journal of Nephrology
Manuscript ID	114239
Country	Australia

Category	Urology & Nephrology
Manuscript Type	Minireviews
Article Title	Immune checkpoint inhibitor-related acute kidney injury: A diagnostic and therapeutic challenge for nephrologists
Manuscript Source	Invited Manuscript
All Author List	Muhammad M Javaid, Gina Tonkin-Hill and Martin Klein
Funding Agency and Grant Number
Corresponding Author	Muhammad M Javaid, Adjunct Associate Professor, Affiliate Associate Professor, Consultant, FASN, FRACP, FRCP, Department of Medicine, South West Healthcare, 25 Ryot Street, Warrnambool 3280, Victoria, Australia. mmjavaid@doctors.org.uk
Key Words	Acute kidney injury; Acute tubulointerstitial nephritis; Immune checkpoint inhibitors; Glomerulonephritis; Nephritis; Nephrotoxicity
Core Tip	Immune-mediated acute kidney injury is rare in cancer patients treated with immune checkpoint inhibitors. The presenting features are non-specific, making it difficult to distinguish from other more commonly encountered pre-renal and post-renal causes. However, a precise diagnosis is imperative for instigating appropriate management plan. Attention to the presence of risk factors and other associated features can guide further investigations. Confirmation of diagnosis with a kidney biopsy can minimise the risk of inappropriate exposure to immunosuppression in already seriously unwell patient.
Citation	Javaid MM, Tonkin-Hill G, Klein M. Immune checkpoint inhibitor-related acute kidney injury: A diagnostic and therapeutic challenge for nephrologists. World J Nephrol 2026; In press

Received	2025-09-15 07:12
Peer-Review Started	2025-09-15 07:12
First Decision by Editorial Office Director	2025-09-29 08:49
Return for Revision	2025-09-29 08:49
Revised	2025-10-25 08:27
Publication Fee Transferred
Second Decision by Editor	2026-01-07 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-01-07 09:59
Articles in Press	2026-01-07 09:59
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-6124 (online)
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