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Publication Name World Journal of Transplantation
Manuscript ID 114278
Country Brazil
Category Transplantation
Manuscript Type Systematic Reviews
Article Title Navigating the landscape of liver transplantation in neuroendocrine tumors: A comprehensive scoping review
Manuscript Source Invited Manuscript
All Author List Leonardo Kasputis Zanini, Eduarda Costa Oliveira, Fabrício Inácio de Moraes Nascimento and Lucas Souto Nacif
Funding Agency and Grant Number
Corresponding Author Lucas Souto Nacif, Chief, Researcher, Department of Liver and Gastrointestinal Transplant, Hospital 9 de Julho, Peixoto Gomide Street, 645-Cerqueira César, São Paulo 01409-002, Brazil. lucasnacif11@gmail.com
Key Words Neuroendocrine tumors; Liver transplantation; Liver neoplasms; Neoplasm metastasis; Hepatectomy
Core Tip Liver transplantation is an established but uncommon treatment for patients with unresectable liver metastases from neuroendocrine tumors. This scoping review mapped the available evidence, identifying 73 studies (case series, retrospective cohorts, and reviews). Reported outcomes suggest improved overall survival in selected patients compared to non-transplant strategies, although data heterogeneity and the lack of high-level evidence limit definitive conclusions. Our findings highlight the need for prospective, multicenter studies and standardized selection criteria to optimize patient outcomes and better define the role of transplantation in this setting.
Citation Zanini LK, Oliveira EC, Nascimento FIM, Nacif LS. Navigating the landscape of liver transplantation in neuroendocrine tumors: A comprehensive scoping review. World J Transplant 2026; In press
Received
2025-09-16 06:33
Peer-Review Started
2025-09-16 06:33
First Decision by Editorial Office Director
2025-09-28 10:41
Return for Revision
2025-09-28 10:41
Revised
2025-10-19 19:18
Publication Fee Transferred
Second Decision by Editor
2026-02-03 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-03 09:50
Articles in Press
2026-02-03 09:50
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2220-3230 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
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