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Publication Name World Journal of Clinical Pediatrics
Manuscript ID 114310
Country India
Category Pediatrics
Manuscript Type Case Report
Article Title Fusobacterium brain abscess as a complication of sinusitis in an immunocompetent adolescent: A case report
Manuscript Source Invited Manuscript
All Author List Janani Sankar, Padma Priya K Haribabu and Ajay Gokhulnathan K Singaravelu Suganya
Funding Agency and Grant Number
Corresponding Author Padma Priya K Haribabu, Academic Fellow, Department of Paediatrics, Kanchi Kamakoti Childs Trust Hospital, No 12 A, Nageswara Road, Tirumurthy Nagar, Nungambakkam, Chennai 600034, Tamil Nādu, India. khpadmapriya@gmail.com
Key Words Brain abscess; Fusobacterium nucleatum; Subdural empyema; Sinusitis; Next-generation sequencing; Status epilepticus; Case report
Core Tip Fusobacterium nucleatum brain abscess is an uncommon but serious complication of sinusitis, especially in immunocompetent children. Conventional cultures often remain sterile because of the organism’s anaerobic nature. This case illustrates the value of 16S rRNA next-generation sequencing (NGS) for rapid pathogen identification and targeted therapy. Early neurosurgical drainage with appropriate anaerobic coverage resulted in full neurological recovery.
Citation Sankar J, Haribabu PPK, Suganya AGKS. Fusobacterium brain abscess as a complication of sinusitis in an immunocompetent adolescent: A case report. World J Clin Pediatr 2025; In press
Received
2025-09-22 02:38
Peer-Review Started
2025-09-22 02:38
First Decision by Editorial Office Director
2025-10-10 09:05
Return for Revision
2025-10-10 09:05
Revised
2025-10-30 17:05
Publication Fee Transferred
Second Decision by Editor
2025-12-15 02:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-15 05:31
Articles in Press
2025-12-15 05:31
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2219-2808 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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