Publication Name	World Journal of Virology
Manuscript ID	114321
Country	India

Category	Virology
Manuscript Type	Review
Article Title	Viral hepatitis after liver transplantation: A brief overview
Manuscript Source	Invited Manuscript
All Author List	Dibya Lochan Praharaj, Suprabhat Giri, Anil Chandra Anand, Bipadabhanjan Mallick, Preetam Nath, Saroj Kanta Sahu, Bramhadatta Pattnaik, Subrat Kumar Acharya and Yogesh Kumar Chawla
Funding Agency and Grant Number
Corresponding Author	Anil Chandra Anand, Professor, Department of Gastroenterology and Hepatology, Kalinga Institute of Medical Sciences, KIIT Campus, Patia, Bhubaneswar 751024, Odisha, India. anilcanand@gmail.com
Key Words	Viral hepatitis; Hepatotropic virus; Liver transplantation; Cytomegalovirus disease; Post-transplant lymphoproliferative disorders
Core Tip	Effective management of viral hepatitis after liver transplantation hinges on early diagnosis, vigilant monitoring, and timely antiviral therapy. For hepatitis B virus, nucleos(t)ide analogues with high genetic barriers to resistance (e.g., entecavir, tenofovir alefnamide/tenofovir disoproxyl fumarate) are preferred, often with short-term hepatitis B immunoglobulin in high-risk patients. Directly acting antivirals have revolutionized treatment of patients with hepatitis C virus infection. Though timing of treatment must balance the baseline model for end stage liver disease score and graft outcomes. Hepatitis E virus infection should be suspected in unexplained graft dysfunction; ribavirin is effective when reduction of immunosupression fails. Recurrence with hepatitis D virus infection is rare if hepatitis B virus is well controlled. Infection with cytomegalovirus and Epstein-Barr virus require prophylaxis, pre-emptive monitoring, and individualized immunosuppression adjustment to reduce risk of post-transplant lymphoproliferative disorder (related to Epstein-Barr virus infection) and graft loss.
Citation	Praharaj DL, Giri S, Anand AC, Mallick B, Nath P, Sahu SK, Pattnaik B, Acharya SK, Chawla YK. Viral hepatitis after liver transplantation: A brief overview. World J Virol 2025; In press

Received	2025-09-18 02:32
Peer-Review Started	2025-09-18 02:33
First Decision by Editorial Office Director	2025-11-10 07:09
Return for Revision	2025-11-10 07:09
Revised	2025-11-22 16:28
Publication Fee Transferred
Second Decision by Editor	2025-12-25 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-25 07:32
Articles in Press	2025-12-25 07:32
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3249 (online)
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