Publication Name	World Journal of Psychiatry
Manuscript ID	114348
Country	China

Category	Psychology
Manuscript Type	Retrospective Study
Article Title	Age-related and sex-related disparities in psychological distress among thyroid cancer patients: A retrospective study
Manuscript Source	Unsolicited Manuscript
All Author List	Wen Li, Yue-Xin Su, Cheng Wang, Yun-Ling Wang, Si-Xian Gao, Jing Bao and Qian-Wen Zhu
Funding Agency and Grant Number	Funding Agency Grant Number Tai'an Science and Technology Innovation Development Project No. 2023NS259
Corresponding Author	Qian-Wen Zhu, Department of Thyroid Surgery, The Second Affiliated Hospital of Shandong First Medical University, No. 366 Taishan Street, Taishan District, Tai’an 271000, Shandong Province, China. zqw1855@163.com
Key Words	Thyroid cancer; Psychological health; Anxiety; Depression; Quality of life; Age; Gender; Influencing factors
Core Tip	This retrospective study explored the influence of age and gender on psychological health in thyroid cancer patients. Results revealed that female and younger patients exhibited significantly higher levels of anxiety and depression and lower quality of life scores compared with males and older patients. Multiple regression analysis confirmed that female sex, young age, advanced TNM stage, and lower education level were independent risk factors for poor psychological outcomes. These findings highlight the need for early psychological screening and tailored intervention strategies for high-risk subgroups to improve overall treatment effectiveness and quality of life.
Citation	Li W, Su YX, Wang C, Wang YL, Gao SX, Bao J, Zhu QW. Age-related and sex-related disparities in psychological distress among thyroid cancer patients: A retrospective study. World J Psychiatry 2025; In press

Received	2025-10-10 08:39
Peer-Review Started	2025-10-10 08:39
First Decision by Editorial Office Director	2025-10-30 06:06
Return for Revision	2025-10-30 06:06
Revised	2025-11-06 15:11
Publication Fee Transferred	2025-11-11 02:49
Second Decision by Editor	2025-12-02 02:47
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-02 10:32
Articles in Press	2025-12-02 10:32
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3206 (online)
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