Publication Name	World Journal of Hepatology
Manuscript ID	114384
Country	Australia

Category	Gastroenterology & Hepatology
Manuscript Type	Letter to the Editor
Article Title	Multidrug-resistant organism colonization in critically ill cirrhotic patients: Marker or mediator of mortality?
Manuscript Source	Invited Manuscript
All Author List	Shi-San Bao and Yan Lu
Funding Agency and Grant Number
Corresponding Author	Shi-San Bao, Department of Pathology, Faculty of Medicine and Health, University of Sydney, D06, Sydney 2006, New South Wales, Australia. profbao@hotmail.com
Key Words	Multidrug-resistant organisms; Cirrhosis; Acute-on-chronic liver failure; Intensive care unit; Mortality
Core Tip	Multidrug-resistant organism colonization is frequent in critically ill cirrhotic patients and strongly predicts subsequent infection. However, colonization alone does not determine mortality, which is primarily driven by organ dysfunction severity. Colonization status remains an important tool for guiding empiric antimicrobial therapy and tailoring stewardship strategies, particularly in regions with distinct epidemiological patterns.
Citation	Bao SS, Lu Y. Multidrug-resistant organism colonization in critically ill cirrhotic patients: Marker or mediator of mortality? World J Hepatol 2025; In press

Received	2025-09-17 06:52
Peer-Review Started	2025-09-17 06:52
First Decision by Editorial Office Director	2025-09-30 09:51
Return for Revision	2025-09-30 10:40
Revised	2025-10-01 10:52
Publication Fee Transferred
Second Decision by Editor	2025-12-17 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-17 08:59
Articles in Press	2025-12-17 08:59
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5182 (online)
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