Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	114390
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Advanced gastric small cell carcinoma with immunotherapy-based treatment: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Xiao-Long Zhang, Jing-Yan Zhang, Ling Xie, Hui Li and Li Wang
Funding Agency and Grant Number
Corresponding Author	Hui Li, Department of Pathology, Affiliated Hospital of Nanjing University of Chinese Medicine, No. 155 Hanzhong Road, Nanjing 210029, Jiangsu Province, China. lihui19830401@163.com
Key Words	Gastric; Small cell carcinoma; Programmed cell death ligand 1; Immunotherapy; Prognosis; Case report
Core Tip	The clinical and pathological characteristics of primary gastric small cell carcinoma (GSCC) resemble those of small cell lung cancer, but it is less sensitive to chemotherapy and has a poor prognosis. Here we report a case of a 67-year-old man who was found to have a primary stage IV GSCC with metastasis to the liver. The patient was treated with chemotherapy combined with a programmed cell death ligand 1 (PD-L1) inhibitor. Whether PD-L1 inhibitors are optimal for metastatic GSCC requires further exploration.
Citation	Zhang XL, Zhang JY, Xie L, Li H, Wang L. Advanced gastric small cell carcinoma with immunotherapy-based treatment: A case report. World J Gastrointest Oncol 2025; In press

Received	2025-09-19 08:51
Peer-Review Started	2025-09-19 08:51
To Make the First Decision
Return for Revision	2025-10-10 03:15
Revised	2025-10-23 13:09
Second Decision	2025-11-13 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-11-13 09:09
Articles in Press	2025-11-13 09:09
Publication Fee Transferred	2025-10-27 01:15
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com