Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	114477
Country	China

Category	Surgery
Manuscript Type	Case Report
Article Title	Gallbladder small cell carcinoma from chronic cholecystitis: A case report and review of literature
Manuscript Source	Unsolicited Manuscript
All Author List	Jia-Qi Yu, Xue-Song He, Yu-Zhe Xue, Ling-Yu Hu, Xu Wen, Xiao-Dan Yang and Xue Zhou
Funding Agency and Grant Number
Corresponding Author	Jia-Qi Yu, PhD, Jiaxing University Master Degree Cultivation Base, Zhejiang Chinese medicial University, 548 Binwen Road, Binjiang District, Hangzhou City, Zhejiang Province, Hangzhou 310053, Zhejiang Province, China. snapeyu@163.com
Key Words	Gallbladder cancer; Chronic calculous cholecystitis; Small cell carcinoma; Surgical treatment; Neuroendocrine tumors; Case report
Core Tip	Gastrointestinal neuroendocrine tumors are relatively common, but gallbladder small cell carcinoma (SCC) is an extremely rare subtype, with limited clinical reports and no established treatment guidelines. Most clinicians manage SCC as gallbladder cancer, yet the 5-year survival rate for early- and mid-stage SCC exceeds 94%, significantly higher than that of typical gallbladder adenocarcinoma. Misdiagnosis and delayed treatment can significantly increase mortality. Due to the rarity of cases, clinicians often lack familiarity with the clinical features and imaging characteristics of gallbladder SCC, leading to diagnostic challenges. This report highlights the importance of timely recognition and radical surgical management to improve outcomes.
Citation	Yu JQ, He XS, Xue YZ, Hu LY, Wen X, Yang XD, Zhou X. Gallbladder small cell carcinoma from chronic cholecystitis: A case report and review of literature. World J Gastrointest Surg 2025; In press

Received	2025-09-22 03:21
Peer-Review Started	2025-09-22 03:21
To Make the First Decision
Return for Revision	2025-10-10 02:37
Revised	2025-10-18 19:56
Second Decision	2025-11-21 02:36
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-11-21 08:21
Articles in Press	2025-11-21 08:21
Publication Fee Transferred	2025-10-20 09:28
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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