Publication Name	World Journal of Gastroenterology
Manuscript ID	114657
Country	United States

Category	Gastroenterology & Hepatology
Manuscript Type	Meta-Analysis
Article Title	Outcomes of liver and cardiovascular metabolic diseases among lean vs non-lean individuals with metabolic dysfunction-associated steatotic liver disease
Manuscript Source	Unsolicited Manuscript
All Author List	Mexan Mapouka, Evariste Pabingui, Nkengeh N Tazinkeng, Milkessa Gurmessa, Ulrich Vickos, Nkafu Betchem Ndemazie and Serge Magloire Camengo Police
Funding Agency and Grant Number
Corresponding Author	Mexan Mapouka, MD, Department of Internal Medicine, University of Maryland Capital Region Medical Center, 901 Harry S Truman Dr, Largo, MD 20774, United States. mexan.mapouka@umm.edu
Key Words	Metabolic dysfunction-associated steatotic liver disease; Lean obesity; Liver fibrosis; Metabolic dysfunction-associated steatohepatitis; Mortality
Core Tip	Metabolic dysfunction-associated steatotic liver disease affects both lean and non-lean individuals. This meta-analysis of over 10 million participants found that non-lean patients had greater odds of hepatic steatosis, fibrosis, cirrhosis, and hypertension. Lean patients, however, showed similar risks of nonalcoholic steatohepatitis, cardiovascular disease, and mortality. These results support expanding metabolic dysfunction-associated steatotic liver disease screening and risk assessment beyond obesity-related criteria.
Citation	Mapouka M, Pabingui E, Tazinkeng NN, Gurmessa M, Vickos U, Ndemazie NB, Camengo Police SM. Outcomes of liver and cardiovascular metabolic diseases among lean vs non-lean individuals with metabolic dysfunction-associated steatotic liver disease. World J Gastroenterol 2026; In press

Received	2025-09-25 06:02
Peer-Review Started	2025-09-25 06:03
First Decision by Editorial Office Director	2025-10-23 08:59
Return for Revision	2025-10-23 08:59
Revised	2025-12-04 18:43
Publication Fee Transferred	2025-12-03 00:44
Second Decision by Editor	2026-02-13 02:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-02-13 07:20
Articles in Press	2026-02-13 07:20
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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