Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	114690
Country	China

Category	Oncology
Manuscript Type	Retrospective Cohort Study
Article Title	Efficacy and safety of integrated Chinese and Western medicine in advanced pancreatic cancer: A double-center retrospective cohort study
Manuscript Source	Unsolicited Manuscript
All Author List	Ying-Rui Wang, Jin-Qiu Wang, Xue-Jiao Chen, Yu Yan, Yu Zhang, Meng-Yi Li, Wei Wang, Tian-Yu Fan, Peng-Fei Jiao and Chao-Feng Zhou
Funding Agency and Grant Number
Corresponding Author	Chao-Feng Zhou, Chief Physician, Department of Oncology, Henan Provincial Hospital of Traditional Chinese Medicine, No. 6 Dongfeng Road, Zhengzhou 450000, Henan Province, China. doctorzcf@126.com
Key Words	Advanced pancreatic cancer; Integrated Chinese and Western medicine; Retrospective cohort study; Survival duration; Short-term outcomes; Long-term outcomes; Safety
Core Tip	Advanced pancreatic cancer (PC) is associated with poor prognosis. In this double-center retrospective cohort study, the median survival time in the Western medicine (WM) group was 10.67 months, while the integration of Chinese and WM group demonstrated an additional 2.24 months of survival. This breakthrough exceeded the conventional 12-month median survival time threshold for PC, nearing the survival outcomes achieved with targeted immunotherapy and combination chemotherapy, which are at the forefront of precision treatments. These findings suggest that integrated Chinese and WM models may provide survival advantages to patients with advanced PC.
Citation	Wang YR, Wang JQ, Chen XJ, Yan Y, Zhang Y, Li MY, Wang W, Fan TY, Jiao PF, Zhou CF. Efficacy and safety of integrated Chinese and Western medicine in advanced pancreatic cancer: A double-center retrospective cohort study. World J Gastrointest Oncol 2025; In press

Received	2025-09-26 11:12
Peer-Review Started	2025-09-26 11:15
First Decision by Editorial Office Director	2025-10-30 09:25
Return for Revision	2025-10-30 10:40
Revised	2025-11-09 11:07
Publication Fee Transferred	2025-11-11 09:37
Second Decision by Editor	2025-12-15 02:45
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-15 06:01
Articles in Press	2025-12-15 06:01
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com