Publication Name	World Journal of Gastroenterology
Manuscript ID	114727
Country	China

Category	Oncology
Manuscript Type	Letter to the Editor
Article Title	Future directions of image-guided thermal ablation in colorectal cancer lung oligometastases
Manuscript Source	Invited Manuscript
All Author List	Yu-Yin Wang, Cui-Ping Zhang, Qing-Biao Zhang, Xing-Yan Le, Jun-Bang Feng and Chuan-Ming Li
Funding Agency and Grant Number
Corresponding Author	Chuan-Ming Li, MD, Professor, Department of Medical Imaging, Chongqing Emergency Medical Center, Chongqing University Central Hospital, School of Medicine, Chongqing University, No. 1 Jiankang Road, Yuzhong District, Chongqing 400014, China. lichuanming@hospital.cqmu.edu.cn
Key Words	Colorectal cancer; Lung oligometastases; Extrapulmonary metastases; Image-guided thermal ablation; Dynamic contrast-enhanced computed tomography; Functional imaging
Core Tip	Colorectal cancer with lung oligometastases, especially when accompanied by extrapulmonary lesions, remains a major therapeutic challenge. Image-guided thermal ablation is a potentially effective minimally invasive local therapy, but current practice has several limitations: The absence of pathological confirmation for some metastatic sites, follow-up dependency on dynamic contrast-enhanced-computed tomography and vulnerability to inflammatory interference, a lack of control groups receiving other standard local treatments, and small sample sizes in certain subgroups. Future studies should improve pathological sampling, incorporate functional imaging, such as fluorodeoxyglucose positron emission tomography/computed tomography, and increase the sample size to provide more reliable evidence for individualized therapy.
Citation	Wang YY, Zhang CP, Zhang QB, Le XY, Feng JB, Li CM. Future directions of image-guided thermal ablation in colorectal cancer lung oligometastases. World J Gastroenterol 2025; In press

Received	2025-09-27 17:20
Peer-Review Started	2025-09-27 17:21
First Decision by Editorial Office Director	2025-10-21 09:34
Return for Revision	2025-10-21 09:35
Revised	2025-10-27 13:19
Publication Fee Transferred
Second Decision by Editor	2025-12-01 02:50
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-02 09:09
Articles in Press	2025-12-02 09:09
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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