Publication Name	World Journal of Gastroenterology
Manuscript ID	114752
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Correlation between sarcopenia and esophageal stenosis following endoscopic submucosal dissection and construction of a postoperative stenosis risk model
Manuscript Source	Unsolicited Manuscript
All Author List	Kai-Zhe Yang, Lu Chen, Li Xu, Bin-Xiang Xu, Ming-Yue Li, Zhi Wang and Qin Lu
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 82300638 General Program of Jiangsu Provincial Administration of Traditional Chinese Medicine MS2024139 Zhongda Hospital Affiliated to Southeast University, Jiangsu Province High-Level Hospital Construction Funds YKK24268
Corresponding Author	Qin Lu, Associate Chief Physician, MD, Research Fellow, Researcher, Department of Gastroenterology, Zhongda Hospital Southeast University, No. 87 Dingjiaqiao, Gulou District, Nanjing 210009, Jiangsu Province, China. luqin81287@163.com
Key Words	Sarcopenia; Endoscopic submucosal dissection; Esophageal stenosis; Complications; Prediction model
Core Tip	A novel finding of this study is that a body composition abnormality, quantified by an index associated with computed tomography-defined sarcopenia, is a clinically significant and independent predictor of the development of esophageal stenosis after endoscopic submucosal dissection (ESD). We successfully constructed a risk prediction model for post-ESD stenosis that includes sarcopenia, which achieved good internal validation. This investigation addresses a limitation of prior research, which focused solely on local lesion characteristics for predicting post-ESD esophageal stenosis. Moreover, the model helps in identifying high-risk groups at early time points and formulating individualized treatment strategies.
Citation	Yang KZ, Chen L, Xu L, Xu BX, Li MY, Wang Z, Lu Q. Correlation between sarcopenia and esophageal stenosis following endoscopic submucosal dissection and construction of a postoperative stenosis risk model. World J Gastroenterol 2025; In press

Received	2025-09-28 10:40
Peer-Review Started	2025-09-28 10:40
First Decision by Editorial Office Director	2025-11-10 07:43
Return for Revision	2025-11-10 07:43
Revised	2025-11-20 20:00
Publication Fee Transferred	2025-11-21 14:55
Second Decision by Editor	2025-12-29 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-29 06:40
Articles in Press	2025-12-29 06:40
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Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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