Publication Name	World Journal of Clinical Oncology
Manuscript ID	114774
Country	China

Category	Oncology
Manuscript Type	Meta-Analysis
Article Title	Correlation between bariatric surgery and breast cancer risk in women: A systematic review and meta-analysis
Manuscript Source	Invited Manuscript
All Author List	Yan-Fei He, Huan-Zhi Wang, Ning Bian, Xiao-Dong Hu, Qin-Tong He, Jun-Qiang Liu, Hu-Ming Li, Shuang-Feng Lu and Ni Wu
Funding Agency and Grant Number
Corresponding Author	Yan-Fei He, Associate Chief Physician, MD, Health Management Center, The Sixth Medical Center, Chinese PLA General Hospital, No. 6 Fu Cheng Road, HaiDian District, Beijing 100048, China. heyanfeilc@163.com
Key Words	Bariatric surgery; Metabolic surgery; Obesity surgery; Roux-en-Y gastric bypass; Breast cancer; Female-specific cancer; Obesity-related cancer; Gastric bypass surgery; Meta-analysis
Core Tip	Obesity is a well-established risk factor for breast cancer. Although bariatric surgery is an effective intervention for long-term weight management and metabolic improvement, its impact on breast cancer incidence remains unclear. Our systematic review and meta-analysis of 17 observational studies indicates that bariatric surgery is associated with an overall reduced risk of breast cancer in obese women. This protective effect was observed in both premenopausal and postmenopausal women, though it was more pronounced in the latter group. However, the observational design precludes establishing causality. An observed increased risk of stage I cancer requires cautious interpretation. These findings offer a new perspective on the potential role of bariatric surgery in reducing breast cancer risk.
Citation	He YF, Wang HZ, Bian N, Hu XD, He QT, Liu JQ, Li HM, Lu SF, Wu N. Correlation between bariatric surgery and breast cancer risk in women: A systematic review and meta-analysis. 2026; World J Clin Oncol In press

Received	2025-09-28 00:29
Peer-Review Started	2025-09-28 00:30
First Decision by Editorial Office Director	2025-11-18 09:54
Return for Revision	2025-11-18 09:54
Revised	2025-11-30 03:04
Publication Fee Transferred
Second Decision by Editor	2026-02-02 02:50
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-02-02 11:08
Articles in Press	2026-02-02 11:08
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2218-4333 (online)
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