Publication Name	World Journal of Critical Care Medicine
Manuscript ID	114792
Country	India

Category	Oncology
Manuscript Type	Minireviews
Article Title	Delirium in the oncology intensive care unit: Risk, recognition, and recovery strategies
Manuscript Source	Invited Manuscript
All Author List	Prashant Sirohiya, Prateek Maurya, Nishkarsh Gupta, Saurabh Vig, Balbir Kumar, Brajesh Kumar Ratre, Raghav Gupta, Shweta Bhopale and Anuja Pandit
Funding Agency and Grant Number
Corresponding Author	Prashant Sirohiya, Assistant Professor, Department of Onco-Anaesthesia and Palliative Medicine, National Cancer Institute, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, Delhi, India. sirohiyaprashant@gmail.com
Key Words	Delirium; Oncology intensive care unit; Cancer critical care; Cognitive dysfunction; Neurological complications; Palliative care; Intensive care unit outcomes; Chemotherapy neurotoxicity; Post-intensive care syndrome; Cancer survivorship
Core Tip	Delirium affects up to 88% of critically ill cancer patients, increasing intensive care units (ICU) mortality tenfold and making post-discharge treatment discontinuation four times more likely. This review introduces the “double burden” of ICU delirium superimposed on chemotherapy-related cognitive impairment, creating unique survivorship challenges. Cancer-specific vulnerabilities include chemotherapy neurotoxicity, central nervous system malignancy, and chimeric antigen receptor T-associated neurotoxicity. Evidence favors non-pharmacologic prevention, with early mobilization reducing delirium by 47%. Delirium thus extends beyond transient confusion to a key determinant of cancer survivorship, potentially transforming ICU admission into a treatment-limiting event.
Citation	Sirohiya P, Maurya P, Gupta N, Vig S, Kumar B, Ratre BK, Gupta R, Bhopale S, Pandit A. Delirium in the oncology intensive care unit: Risk, recognition, and recovery strategies. World J Crit Care Med 2026; In press

Received	2025-09-28 08:31
Peer-Review Started	2025-09-28 08:31
First Decision by Editorial Office Director	2025-10-10 09:06
Return for Revision	2025-10-10 09:06
Revised	2025-10-21 09:20
Publication Fee Transferred
Second Decision by Editor	2026-01-28 02:36
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-01-28 10:36
Articles in Press	2026-01-28 10:36
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3141(online)
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