Publication Name	World Journal of Immunology
Manuscript ID	114815
Country	India

Category	Infectious Diseases
Manuscript Type	Opinion Review
Article Title	Body size and infection: An immunological balancing act
Manuscript Source	Invited Manuscript
All Author List	Binod Kumar Pati and Prasan Kumar Panda
Funding Agency and Grant Number
Corresponding Author	Prasan Kumar Panda, Professor, Department of Medicine, All India Institute of Medical Sciences, Room No. 409, Building No 1, Rishikesh 249203, India. motherprasanna@rediffmail.com
Key Words	Host-pathogen interactions; Immune system phenomena; Microbiota; Anatomical barriers; Evolutionary biology; Antimicrobial resistance
Core Tip	Pathogen and host dimensions - from nanometer molecules to meter-long structures - govern the strategies of infection, immunity, and survival. Nanometric viruses to larger helminths are countered by host defenses, such as molecular mediators, phagocytes, and anatomical barriers. Furthermore, time pressure links size driven microbial adaptation, including antimicrobial resistance, into host tolerance and immunity. Recognizing size as a central determinant in host-microbe interactions provides new insights into susceptibility, antimicrobial resistance, and opportunities for precision medicine.
Citation	Pati BK, Panda PK. Body size and infection: An immunological balancing act. World J Immunol 2026; In press

Received	2025-09-29 01:24
Peer-Review Started	2025-09-29 01:24
First Decision by Editorial Office Director	2025-10-10 09:11
Return for Revision	2025-10-10 09:11
Revised	2025-10-23 02:30
Publication Fee Transferred
Second Decision by Editor	2026-01-06 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-01-07 00:56
Articles in Press	2026-01-07 00:56
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2219-2824 (online)
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