Publication Name	World Journal of Psychiatry
Manuscript ID	114859
Country	China

Category	Psychiatry
Manuscript Type	Retrospective Cohort Study
Article Title	Long-term psychiatric and neurodevelopmental profiles of children with global developmental delay
Manuscript Source	Unsolicited Manuscript
All Author List	Lin Li, Xue-Ping Zhang and Ying-Ai Zheng
Funding Agency and Grant Number
Corresponding Author	Ying-Ai Zheng, MD, Department of Pediatrics, Ninghai Maternal and Child Health Hospital, Ningbo 315600, Zhejiang Province, China. zhengyingai081@126.com
Key Words	Global developmental delay; Psychiatric comorbidity; Neurodevelopmental outcomes; Longitudinal study; Early intervention
Core Tip	Global developmental delay (GDD) affects up to 3% of children and is frequently complicated by psychiatric comorbidities, which may worsen long-term outcomes. In this 2-year retrospective cohort study of 100 children with GDD, 68% developed psychiatric disorders, most commonly attention deficit/hyperactivity disorder, autism spectrum disorder, and anxiety. Children with multiple psychiatric comorbidities demonstrated significantly poorer developmental quotients compared to those without comorbidities. Early intervention, particularly in language and social domains, improved developmental outcomes. These findings highlight the importance of early psychiatric screening and integrated intervention strategies to optimize trajectories in children with GDD.
Citation	Li L, Zhang XP, Zheng YA. Long-term psychiatric and neurodevelopmental profiles of children with global developmental delay. World J Psychiatry 2026; In press

Received	2025-10-31 08:49
Peer-Review Started	2025-10-31 08:49
First Decision by Editorial Office Director	2025-11-21 06:19
Return for Revision	2025-11-21 06:19
Revised	2025-11-30 09:31
Publication Fee Transferred	2025-12-03 02:07
Second Decision by Editor	2026-01-08 02:47
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-01-08 04:57
Articles in Press	2026-01-08 04:57
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3206 (online)
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