Publication Name	World Journal of Nephrology
Manuscript ID	114871
Country	Pakistan

Category	Urology & Nephrology
Manuscript Type	Retrospective Study
Article Title	Temporal trends and disparities in stroke mortality among adults with chronic kidney disease in the United States, 1999-2020
Manuscript Source	Invited Manuscript
All Author List	Muhammad Ibrahim, Malik Aqeel Ahmad, Ayesha Mansoor, Husnain Ali and FNU Sahil
Funding Agency and Grant Number
Corresponding Author	Muhammad Ibrahim, Academic Fellow, Doctorate Student, Honorary Research Fellow, MD, Researcher, Senior Researcher, Department of Nephrology, Faislabad Medical University, Faisalabad - Samundri Road, Faisalabad, Pakistan, Faisalabad 38000, Punjab, Pakistan. mi0100042@gmail.com
Key Words	Stroke; Chronic kidney disease; Epidemiology; Mortality; CDC WONDER
Core Tip	This national study examines 22-year trends in stroke mortality among United States adults with chronic kidney disease (CKD), a high-risk population often overlooked in cerebrovascular research. Using population-level mortality data, we identified periods of both decline and resurgence in mortality, along with striking disparities by sex, race/ethnicity, region, and urbanization. Non-Hispanic Black individuals and residents of small metropolitan areas experienced the greatest burden. These findings highlight evolving epidemiologic patterns and the urgent need for targeted, equity-driven interventions to reduce stroke mortality in adults with CKD.
Citation	Ibrahim M, Ahmad MA, Mansoor A, Ali H, Sahil F. Temporal trends and disparities in stroke mortality among adults with chronic kidney disease in the United States, 1999-2020. World J Nephrol 2025; In press

Received	2025-09-30 02:10
Peer-Review Started	2025-09-30 02:10
To Make the First Decision
Return for Revision	2025-10-18 02:21
Revised	2025-10-26 12:44
Second Decision	2025-11-14 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-11-14 04:25
Articles in Press	2025-11-14 04:25
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-6124 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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