| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Latent tuberculosis screening for inflammatory bowel disease in tuberculosis endemic region remains porous and suboptimal: A multicentre study
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Daya Krishna Jha, Shilpa Prasad, Arun Valsan, Shubhra Mishra, Priya Nair, Anoop K Koshy, Sonal Singh, Ajay Shankar Prasad, Rajat Shukla, Rizwan Ahamed, Philip Augustine, Kartik Natarajan, Kiran Peddi, Akshay Kulkarni, Sumit Bhatia, Aditya V Pachisia, Pradeep K Singh, Anuraag Jena, Swatantra Gupta, Shubham Jain, Kodavoor Padmaprakash, Rinkalben Kakadiya, Amit Kumar, Siddharth Shukla, Usha Dutta, Vivek Hande, Sandeep Thareja and Vishal Sharma |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Vishal Sharma, Additional Professor, DM, Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Sector 12, Chandigarh 160012, India. sharma.vishal@pgimer.edu.in |
| Key Words |
Tuberculosis; Inflammatory bowel disease; Advanced therapy; Ulcerative colitis; Crohn’s disease |
| Core Tip |
This multicenter study about inflammatory bowel disease patients on advanced therapy suggests that compliance with standard latent tuberculosis (LTB) screening, as recommended by LTB guidelines, is low at around 60%. Annual screening for LTB was found to be grossly neglected at 27%. Incidence of LTB was 10.7% and active tuberculosis (TB) developed in 4.5% of the patients on advanced therapy. Other interesting finding was occurrence of active TB with any advanced therapy, suggesting that there is no ‘safe’ therapy in TB endemic regions. |
| Citation |
Jha DK, Prasad S, Valsan A, Mishra S, Nair P, Koshy AK, Singh S, Prasad AS, Shukla R, Ahamed R, Augustine P, Natarajan K, Peddi K, Kulkarni A, Bhatia S, Pachisia AV, Singh PK, Jena A, Gupta S, Jain S, Padmaprakash K, Kakadiya R, Kumar A, Shukla S, Dutta U, Hande V, Thareja S, Sharma V. Latent tuberculosis screening for inflammatory bowel disease in tuberculosis endemic region remains porous and suboptimal: A multicentre study. World J Gastroenterol 2025; In press |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
