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Publication Name World Journal of Clinical Pediatrics
Manuscript ID 114953
Country Thailand
Category Nutrition & Dietetics
Manuscript Type Randomized Controlled Trial
Article Title Clinical outcomes of two lactose-free formulas in the management of acute childhood diarrhea
Manuscript Source Unsolicited Manuscript
All Author List Nopaorn Phavichitr, Ruangvith Tantibhaedhyangkul, Termpong Dumrisilp, Sittichoke Prachuapthunyachart, Wilaiporn Chanpreecha, Panjachat Ratanamongkol and Voranush Chongsrisawat
Funding Agency and Grant Number
Corresponding Author Voranush Chongsrisawat, MD, Professor, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, 1873, Rama 4 Road, Pathumwan, Bangkok 10330, Thailand. voranush.c@chula.ac.th
Key Words Acute diarrhea; Acute gastroenteritis; Children; Lactose-free formula; Nutritional management
Core Tip This randomized controlled trial compared a medium-chain triglyceride-containing lactose-free formula (MLF) with a standard lactose-free formula in children hospitalized with acute diarrhea. MLF showed noninferior efficacy and safety compared to standard lactose-free formula, with similar clinical outcomes and caregiver satisfaction, but at significantly lower cost. MLF may therefore serve as a cost-effective alternative for managing acute diarrhea in young children, particularly in resource-limited settings.
Citation

Phavichitr N, Tantibhaedhyangkul R, Dumrisilp T, Prachuapthunyachart S, Chanpreecha W, Ratanamongkol P, Chongsrisawat V. Clinical outcomes of two lactose-free formulas in the management of acute childhood diarrhea. World J Clin Pediatr 2026; 15(1): 114953

Received
2025-10-11 05:40
Peer-Review Started
2025-10-11 05:40
First Decision by Editorial Office Director
2025-10-30 08:53
Return for Revision
2025-10-30 08:53
Revised
2025-11-13 15:01
Publication Fee Transferred
2025-11-17 11:33
Second Decision by Editor
2026-01-05 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-05 06:48
Articles in Press
2026-01-05 06:48
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-29 01:12
ISSN 2219-2808 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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