Publication Name	World Journal of Orthopedics
Manuscript ID	114984
Country	China

Category	Orthopedics
Manuscript Type	Case Control Study
Article Title	Risk factors for thoracic-osteoporotic thoracic vertebral compression fractures during the normalized prevention and control period of COVID-19
Manuscript Source	Unsolicited Manuscript
All Author List	Yi-Fan Li, Chen-Qiong Wu, Yang Long, Qi-Feng Yu, Wei Xu, Jian-Jie Zhao, Xiang-Yang Zhang and Zhi-Kun Li
Funding Agency and Grant Number	Funding Agency Grant Number Shanghai Municipal Health Commission 2022YQ006 Doctoral Innovation Base Project in Changning District RCJD2022S02
Corresponding Author	Zhi-Kun Li, MD, PhD, Department of Spine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No. 1111 Xianxia Road, Shanghai 200080, China. lizhikun@shsmu.edu.cn
Key Words	COVID-19; Normalized prevention and control; Osteoporotic vertebral compression fracture; Risk factor; Cough
Core Tip	During the normalized prevention and control period of coronavirus disease 2019, compared with cases in the same period, cough is the main cause of osteoporotic vertebral compression fracture (OVCF), and most fractures are thoracic fractures. After percutaneous vertebroplasty treatment, the improvement of pain and function in patients is not significantly different from that in the same period. Regression analysis shows that cause of fracture, nucleic acid test result, body mass index, and bone mineral density are independent risk factors for thoracic OVCF. For elderly COVID-19-positive patients with recurrent cough, timely and active treatment of lung diseases, aggressive anti-osteoporosis therapy, and wearing a thoracic brace for protection are effective measures to prevent thoracic OVCF.
Citation	Li YF, Wu CQ, Long Y, Yu QF, Xu W, Zhao JJ, Zhang XY, Li ZK. Risk factors for thoracic-osteoporotic thoracic vertebral compression fractures during the normalized prevention and control period of COVID-19. World J Orthop 2025; In press

Received	2025-10-11 08:54
Peer-Review Started	2025-10-11 08:54
First Decision by Editorial Office Director	2025-10-23 08:24
Return for Revision	2025-10-23 08:24
Revised	2025-10-30 14:49
Publication Fee Transferred	2025-11-01 13:37
Second Decision by Editor	2025-12-08 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-08 09:28
Articles in Press	2025-12-08 09:28
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Typeset the Manuscript

ISSN	2218-5836 (online)
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