Publication Name	World Journal of Methodology
Manuscript ID	115003
Country	China

Category	Surgery
Manuscript Type	Randomized Controlled Trial
Article Title	Randomized controlled trial of Danggui Sini Decoction in the treatment of lower limb arteriosclerosis obliterans
Manuscript Source	Invited Manuscript
All Author List	Yan-Bo Fu, Feng Yan, Hong-Jiang Zhu and Cong Wang
Funding Agency and Grant Number	Funding Agency Grant Number 2023 Zhangjiajie Municipal Special Fund for Sci-Tech Development No. 7
Corresponding Author	Hong-Jiang Zhu, MD, Department of Vascular Interventional Surgery, Zhangjiajie People’s Hospital, No. 192 Guyong Road, Yongding District, Zhangjiajie 415000, Hunan Province, China. 13028176178@163.com
Key Words	Arteriosclerosis obliterans; Danggui Sini Decoction; Endovascular revascularization; Clinical efficacy; Primary patency rate; Quality of life; Target lesion revascularization
Core Tip	This randomized controlled trial demonstrates that adjunctive therapy with Danggui Sini Decoction (DGSD), a classic traditional Chinese medicine formula, significantly enhances the long-term outcomes of endovascular revascularization for arteriosclerosis obliterans. At six months, the DGSD group showed superior clinical effectiveness (94.74% vs 73.68%) and primary patency rates compared to the control group. The combination therapy also led to a greater improvement in quality of life, suggesting DGSD is a valuable complementary treatment for improving vascular patency and patient well-being in arteriosclerosis obliterans management.
Citation	Fu YB, Yan F, Zhu HJ, Wang C. Randomized controlled trial of Danggui Sini Decoction in the treatment of lower limb arteriosclerosis obliterans. World J Methodol 2026; In press

Received	2025-10-11 09:47
Peer-Review Started	2025-10-11 09:47
First Decision by Editorial Office Director	2025-11-05 08:14
Return for Revision	2025-11-05 08:14
Revised	2025-11-19 02:29
Publication Fee Transferred
Second Decision by Editor	2026-02-02 02:43
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-02-02 07:16
Articles in Press	2026-02-02 07:16
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2222-0682 (online)
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