Publication Name	World Journal of Gastrointestinal Endoscopy
Manuscript ID	115008
Country	India

Category	Gastroenterology & Hepatology
Manuscript Type	Editorial
Article Title	Large colorectal lesions: Expanding the boundaries of endoscopic management
Manuscript Source	Invited Manuscript
All Author List	Amit Bagrodia, Venkatesh Vaithiyam and Supraja Laguduva Mohan
Funding Agency and Grant Number
Corresponding Author	Venkatesh Vaithiyam, DM, MD, Department of Gastroenterology, Govind Ballabh Pant Institute of Post Graduate Medical Education and Research, 1, JLN Marg, Raj Ghat,, New Delhi 110002, Delhi, India. venkateshvaithiyam172@gmail.com
Key Words	Large colorectal lesion; Endoscopic management; Endoscopic mucosal resection; Endoscopic submucosal dissection; Endoscopic full thickness resection; Laterally spreading tumors
Core Tip	Large colorectal lesions constitute a distinct group with increased potential for malignancy, and their removal is technically challenging for endoscopists. Endoscopic mucosal resection is fundamental for many benign lesions; however, the risk of recurrence necessitates complete resection of lesion margins. Endoscopic submucosal dissection provides higher en bloc rates with oncological safety, whereas endoscopic full-thickness resection is beneficial for non-lifting or fibrotic lesions within the device’s limits. Consolidated evidence, including that of Zhu et al, emphasizes that tumor size alone should not dictate surgery; careful patient selection, expertise, and structured surveillance can improve endoscopic outcomes while maintaining bowel continuity.
Citation	Bagrodia A, Vaithiyam V, Large colorectal lesions: Expanding the boundaries of endoscopic management. World J Gastrointest Endosc 2025; In press

Received	2025-10-09 02:31
Peer-Review Started	2025-10-09 02:31
First Decision by Editorial Office Director	2025-11-04 08:03
Return for Revision	2025-11-04 08:03
Revised	2025-11-14 15:25
Publication Fee Transferred
Second Decision by Editor	2025-12-02 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-03 01:39
Articles in Press	2025-12-03 01:39
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5190 (online)
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