Publication Name	World Journal of Gastroenterology
Manuscript ID	115040
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Observational Study
Article Title	Antibiotic consumption of inpatients with inflammatory bowel disease during 2015-2024 and future prediction: Evidence from a general hospital
Manuscript Source	Unsolicited Manuscript
All Author List	Wen Zeng, Wei-Kun Zhang, Duo Xu, Kun He, Yu-Ping Huang, Yu-Xi Liu and Hui-Fang Yang
Funding Agency and Grant Number	Funding Agency Grant Number Natural Science Foundation of Hunan Province No. 2024JJ7477 Shaoyang Science and Technology Plan Project No. 2024GZ2025
Corresponding Author	Hui-Fang Yang, MD, College of Public Health, Ningxia Medical University, No. 1160 Victory Street, Yinchuan 750004, Ningxia Hui Autonomous Region, China. joyceyhf@163.com
Key Words	Inflammatory bowel disease; Inpatients; Ulcerative colitis; Crohn’s disease; Antibiotic consumption; Monte Carlo simulation
Core Tip	This retrospective study analyzed antibiotic consumption of hospitalized Inflammatory bowel disease patients and predicted future trends. Among hospitalized patients, the usage of antibiotics was higher in elderly patients, male patients, and those with ulcerative colitis. The study also found that although the overall usage rate has declined in recent years, the use of “last-resort” antibiotics has significantly increased. The Monte Carlo simulation predicts that antibiotic consumption will double by 2027. These findings indicate an urgent need for targeted antimicrobial management.
Citation	Zeng W, Zhang WK, Xu D, He K, Huang YP, Liu YX, Yang HF. Antibiotic consumption of inpatients with inflammatory bowel disease during 2015-2024 and future prediction: Evidence from a general hospital. World J Gastroenterol 2025; In press

Received	2025-10-11 16:29
Peer-Review Started	2025-10-11 16:29
First Decision by Editorial Office Director	2025-11-11 09:47
Return for Revision	2025-11-11 09:47
Revised	2025-11-21 12:24
Publication Fee Transferred	2025-11-28 14:53
Second Decision by Editor	2025-12-29 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-29 06:52
Articles in Press	2025-12-29 06:52
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Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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