Publication Name	World Journal of Hepatology
Manuscript ID	115060
Country	Australia

Category	Gastroenterology & Hepatology
Manuscript Type	Observational Study
Article Title	Shifting cirrhosis phenotype with changes in liver disease etiology in an Australian tertiary hospital
Manuscript Source	Invited Manuscript
All Author List	Ryma Terbah, Chris Zhao, Tessa Greeve, Elise Cannan, Darren Wong, Adam Testro, Avik Majumdar and Marie Sinclair
Funding Agency and Grant Number
Corresponding Author	Marie Sinclair, Associate Professor, FRACP, PhD, Department of Gastroenterology and Liver Transplantation, Austin Health, 145 Studley Road, Heidelberg, Melbourne 3084, Victoria, Australia. marie.sinclair@austin.org.au
Key Words	Cirrhosis; Etiology; Complications; Ascites; Hepatitis C
Core Tip	Effective treatment is now available for chronic hepatitis C, and as a result, hospitalisation of patients with hepatitis C-related cirrhosis is decreasing, while metabolic-associated steatotic liver disease is rapidly becoming one of the most common causes of cirrhosis requiring hospital admission to a major tertiary hospital in Australia. The phenotype of patients with cirrhosis is also shifting, with a decreasing incidence rate of ascites and hepatic encephalopathy and increasing incidence of non-variceal bleeding. Information on the shifting etiologies, phenotypes and prevalence of complications of cirrhosis is helpful for planning future resource allocation and devising novel ways of managing these patients.
Citation	Terbah R, Zhao C, Greeve T, Cannan E, Wong D, Testro A, Majumdar A, Sinclair M. Shifting cirrhosis phenotype with changes in liver disease etiology in an Australian tertiary hospital. 2026; World J Hepatol In press

Received	2025-10-13 07:26
Peer-Review Started	2025-10-13 07:26
First Decision by Editorial Office Director	2025-10-21 07:36
Return for Revision	2025-10-21 07:36
Revised	2025-11-20 12:55
Publication Fee Transferred
Second Decision by Editor	2026-02-02 02:51
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-02-02 13:19
Articles in Press	2026-02-02 13:19
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5182 (online)
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