Publication Name	World Journal of Hepatology
Manuscript ID	115063
Country	Indonesia

Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Diagnostic challenges of clinically significant portal hypertension in geriatric metabolic dysfunction-associated fatty liver disease: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Femmy Nurul Akbar, Nikko Darnindro, Annisa Ayu Wardhani, Safira Rosiana Choirida, Shafa Nada Saphira, Griffith Ismed, Ida Ayu Made Kshanti, Syifa Mustika and Hari Hendarto
Funding Agency and Grant Number
Corresponding Author	Femmy Nurul Akbar, Associate Professor, Department of Internal Medicine, Faculty of Medicine, Universitas Islam Negeri Syarif Hidayatullah Jakarta, Ir H. Juanda Street No.95, Ciputat District, South Tangerang 15412, Banten, Indonesia. femmy.nurul@uinjkt.ac.id
Key Words	Metabolically-dysfunction-associated fatty liver disease; Liver cirrhosis; Clinically significant portal hypertension; Hepatic fibrosis assessment; Geriatric patients; Case report
Core Tip	Metabolic dysfunction-associated fatty liver disease (MAFLD) is a chronic condition characterized by excess fat accumulation in the liver along with at least one cardiometabolic risk factor. MAFLD can progress silently to liver cirrhosis, often without noticeable symptoms, until clinically significant portal hypertension (CSPH) develops. CSPH can develop early in MAFLD, even before advanced hepatic fibrosis or cirrhosis sets in. We reported a case of a geriatric patient with MAFLD who had CSPH. Following variceal ligation and medical treatment, the patient showed notable improvement. However, diagnosing such cases in daily clinical practice remains quite challenging.
Citation	Akbar FN, Darnindro N, Wardhani AA, Choirida SR, Saphira SN, Ismed G, Kshanti IAM, Mustika S, Hendarto H. Diagnostic challenges of clinically significant portal hypertension in geriatric metabolic dysfunction-associated fatty liver disease: A case report. World J Hepatol 2025; In press

Received	2025-10-13 08:08
Peer-Review Started	2025-10-13 08:08
First Decision by Editorial Office Director	2025-10-29 08:32
Return for Revision	2025-10-29 08:32
Revised	2025-11-12 02:43
Publication Fee Transferred	2025-11-18 12:17
Second Decision by Editor	2025-12-16 02:44
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-16 07:15
Articles in Press	2025-12-16 07:15
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5182 (online)
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