Publication Name	World Journal of Hepatology
Manuscript ID	115108
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Predicting pancreatic fistula post-splenectomy in cirrhosis with splenomegaly: Risk factors and nomogram validation
Manuscript Source	Unsolicited Manuscript
All Author List	Long Huang, Qing-Lin Li, Qing-Sheng Yu, Hui Peng, Zhou Zhen, Qi Zhang and Yi Shen
Funding Agency and Grant Number	Funding Agency Grant Number Projects of Anhui Provincial Health Commission No. AHWJ2023A30146 Scientific Research Projects in Anhui Provincial Colleges and Universities No. 2024AH050959 Anhui Provincial Natural Science Foundation No. 2408085MH222
Corresponding Author	Long Huang, MD, Professor, Department of Hepatobiliary Surgery, The First Hospital Affiliated to Anhui University of Traditional Chinese Medicine, No. 117 Meishan Road, Hefei 230031, Anhui Province, China. huanglong658@163.com
Key Words	Pancreatic fistula; Splenectomy; Splenomegaly; Risk factors; Nomogram
Core Tip	This retrospective study included 186 cirrhotic patients with splenomegaly who underwent splenectomy. Through multivariate least absolute shrinkage and selection operator-penalized logistic regression, body mass index and splenic thickness were confirmed as independent risk factors for clinically relevant postoperative pancreatic fistula. The nomogram built on these factors achieved an area under the receiver operating characteristic curve of 0.816, providing reliable individualized perioperative risk prediction to cut clinically relevant postoperative pancreatic fistula occurrence and boost patient recovery.
Citation	Huang L, Li QL, Yu QS, Peng H, Zhen Z, Zhang Q, Shen Y. Predicting pancreatic fistula post-splenectomy in cirrhosis with splenomegaly: Risk factors and nomogram validation. World J Hepatol 2026; In press

Received	2025-10-13 11:32
Peer-Review Started	2025-10-13 11:33
First Decision by Editorial Office Director	2025-10-30 08:32
Return for Revision	2025-10-30 14:03
Revised	2025-11-10 16:01
Publication Fee Transferred	2025-11-11 12:09
Second Decision by Editor	2026-01-07 02:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-01-07 03:40
Articles in Press	2026-01-07 03:40
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5182 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com